Oocyte and Embryo Quality: Effect of Origin, Culture Conditions and Gene Expression Patterns
P Lonergan,
D Rizos,
A Gutierrez-Adan,
T Fair,
MP Boland,
P Lonergan
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorD Rizos
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorA Gutierrez-Adan
Dpto. de Reproducción Animal y Conservación de Recursos Zoogenéticos, INIA, Ctra de la Coruña Km 5.9, Madrid 28040, Spain
Search for more papers by this authorT Fair
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorMP Boland
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorP Lonergan,
D Rizos,
A Gutierrez-Adan,
T Fair,
MP Boland,
P Lonergan
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorD Rizos
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorA Gutierrez-Adan
Dpto. de Reproducción Animal y Conservación de Recursos Zoogenéticos, INIA, Ctra de la Coruña Km 5.9, Madrid 28040, Spain
Search for more papers by this authorT Fair
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorMP Boland
Department of Animal Science and Production, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland
Search for more papers by this authorFirst published: 29 July 2003
Authors' address (for correspondence): Dr P Lonergan, Department of Animal Science and Production, University College Dublin, Lyons Research Farm, Newcastle, County Dublin, Ireland.
Lonergan, P., Rizos, D., Gutierrez-Adan, A., Fair, T. and Boland, M. (2003), Oocyte and Embryo Quality: Effect of Origin, Culture Conditions and Gene Expression Patterns. Reproduction in Domestic Animals, 38: 259-267. https://doi.org/10.1046/j.1439-0531.2003.00437.x
Contents
In general, the majority of immature bovine oocytes fail to develop to the blastocyst stage following maturation, fertilization and culture in vitro. The evidence suggests that while culture conditions during in vitro embryo production can impact on the developmental potential of the early embryo, the intrinsic quality of the oocyte is the key factor determining the proportion of oocytes developing to the blastocyst stage. In addition, evidence suggests that the period of post-fertilization embryo culture is the most critical in determining blastocyst quality. This paper reviews the current literature, with emphasis on the bovine model, demonstrating evidence for an effect of oocyte origin and/or in vitro maturation conditions on the developmental capacity and gene expression patterns in the oocyte. Furthermore, the well-documented effects of post-fertilization culture environment on embryo gene expression and quality are highlighted.
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Elkins, L. J., & Spiegelman, M. (2021). pyUserCalc: A revised Jupyter notebook calculator for uranium-series disequilibria in basalts. Earth and Space Science, 8, e2020EA001619. https://doi.org/10.1029/2020EA001619
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