drug that affects multiple receptors of the body, with no specific target
1
potent
2
semi-selective
3
cardioselective
4
nonselective
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Terms in this set (23)
Hypertension
high blood pressure
essential hypertension
High blood pressure with no verifiable physical cause, which makes up the overwhelming majority of high blood pressure cases.
orthostatic hypertension
sudden increase in blood pressure when a person stands up
secondary hypertension
high blood pressure caused by the effects of another disease
Hypotension
low blood pressure
Adrenergic Receptors
receptor sites for the sympathetic neurotransmitters norepinephrine and epinephrine
agonists
drugs which mimic the activity of neurotransmitters
Angina
chest pain
Antagonists (drugs)
These drugs block the actions of neurotransmitters
antihypertensive therapy
Medications used to treat hypertension
adrengeric blocking medications
beta blockers ! block the effects of epinephrine and norepinephrine -> decreasing BP and HR
alpha antagonist
alpha 1 antagonist- block alpha 2 receptors found in smooth muscle
alpha 2 antagonist- block alpha 2 receptors found in CNS and tissues
alpha 2 antagonist- block alpha 2 receptors found in CNS and tissues
beta 1 blocker
affects the heart
beta 2 blocker
affects the lungs
Cardiac Output
heart rate x stroke volume
Centrally acting adrenergic medications
Drugs that modify the function of the sympathetic nervous system in the brain by stimulating alpha2 receptors. Alpha2 receptors are inhibitory in nature and thus have a reverse sympathetic effect and cause decreased blood pressure and HR
Dysrhythmias
abnormal or irregular heartbeat
first-dose phenomenon
sudden drop in BP due to the intake of first dose of a new medication; can result in collapsing
intrinsic sympathomimetic activity
beta-blockers' ability to slightly activate the receptors they are trying to block -> blocks stress of some hormones, while stimulating intrinsic effects-> less pronounced HR
nonselective
drug that affects multiple receptors of the body, with no specific target
selective
drug targets specific receptors-> less likely to have a lot of side effects
sympatholytics
mechanisms that reduce the amount of norepinephrine released / inhibit the effects of sympathetic NS
vasodilation
Dilation of blood vessels -> increasing blood flow
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