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Health

We're closing in on how genetics may influence your PCOS risk

In the largest genetic analysis of polycystic ovary syndrome to date, scientists have identified new variants linked to the condition, which could help us treat it more effectively

By Carissa Wong

4 November 2025

An illustration of polycystic ovary syndrome, which causes the ovaries to enlarge

An illustration of polycystic ovary syndrome, which causes the ovaries to enlarge

Science Photo Library / Alamy

We are finally getting to grips with the genetics of polycystic ovary syndrome (PCOS), which could open the door to new treatments.

PCOS, which is thought to affect up to 1 in 5 women, disrupts how ovaries function, resulting in at least two of three features: irregular or no periods; raised levels of male sex hormones, including testosterone; and a build-up of immature eggs that look like cysts in the ovaries. As a result, fertility problems are common with the condition.

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