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Case Records of the Massachusetts General Hospital

Case 29-2025: A 43-Year-Old Woman with Depression, Suicidal Ideation, and Fever

Authors: Michael S. Abers, M.D., Robert J. Lawson, M.D., Sandra B. Nelson, M.D. https://orcid.org/0000-0002-1949-7884, and Melanie C. Kwan, M.D.Author Info & Affiliations
Published October 15, 2025
N Engl J Med 2025;393:1522-1531
DOI: 10.1056/NEJMcpc2412536
VOL. 393 NO. 15

Abstract

A 43-year-old woman with bipolar disorder and advanced HIV infection was admitted to this hospital because of depressed mood, suicidal ideation, cough, and a temperature of 39.5°C. A diagnosis was made.

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Notes

This case was presented at Medicine Grand Rounds.
Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Supplementary Material

Disclosure Forms (nejmcpc2412536_disclosures.pdf)

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