Determined to improve stem cell treatment in Japan, ``Provide safe stem cell treatment according to world standards''

Currently, stem cell treatment clinics in Japan other than our hospital mainly culture and administer one type of stem cells (mostly derived from fat). Of course, I am not saying that this method is bad, but in reality, this method of administration is actually in the minority worldwide. This is mostly done at clinics in Asia, including Japan.

The reason for this is that in Japan, there are almost no opportunities to systematically learn about stem cell therapy, except in some fields such as hematology. If this is the first time for a doctor to perform stem cell treatment, the doctor will pay money to a "medical consultant" who does not have systematic medical training and will be responsible for introducing stem cell treatment. They will tell you things like that. Then, in the case of Japan, clinics that provide similar treatments, such as ``cultivating and administering one type of stem cells (mostly derived from fat)'' that medical consultants can advise, are popping up like Kintaro candy. (Then, in rare cases, people who don't have much knowledge about stem cell therapy will ask such silly questions. Why don't you do standard treatment?'' (I think you can understand the answer from the above explanation)

In reality, neither the medical consultant nor the doctor in question knows that there is actually more than one type of stem cell, and that there are many other types of stem cell treatment. Try asking questions like, ``What types of stem cells do you use at your clinic, and in what cases are stem cell treatments using other types used worldwide? What are the advantages and disadvantages of each?”

But is that really enough? The biggest problem is that measures to prevent side effects are extremely inadequate compared to world standards.

``The safest type of stem cell therapy (mononuclear cell whole stem cell transplantation) is not being performed in the first place,'' and ``necessary safety measures are not being taken when performing cultured stem cell therapy, which requires greater consideration of safety.'' It depends.

Let's take a look at the paper that conducted a cross-sectional study of various types of stem cell therapy: Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials.

The report concluded that regenerative medicine, such as the one we perform at our hospital, is safe. However, it also concluded that there are safety considerations to be taken with other stem cell therapies, and that appropriate safety measures must be taken to ensure patient safety.

The paper Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines:January 30, 2019 states that some stem cells may be more susceptible to causing blood clots due to changes in stem cells caused by culture . It states that stem cells with certain blood clot-inducing factors must be removed before administration, and that a blood compatibility test must be performed before administration .

Naturally, our hospital conducts the above safety tests in all cases, but as far as we know, our hospital is the only one in Japan that does so.

Our hospital provides stem cell treatment for incurable diseases for which there are almost no treatment options, while ensuring the absolute safety mentioned above. We offer stem cell treatment by experienced doctors. In particular, we have the largest number of cases in Japan as a private facility for pediatric stem cell treatment for autism, cerebral palsy, type 1 diabetes, etc.

When providing advanced medical care, I believe that it is dangerous for one doctor to do something based on his own complacency. At our hospital, we place great importance on ensuring that the treatment policy, method, and safety are reasonable from the perspective of multiple doctors, and that we bring together doctors with sufficient skills to deal with any unexpected risks.

In other words, we would like to provide cutting-edge stem cell treatment at the "Team Japan Tokyo Stem Cell Transplantation Treatment Institute." Our team is made up of only doctors who are recognized by other doctors as having "sufficient experience in stem cell treatment."

*This website lists treatments that are only available at overseas clinics and not in Japan.

Japan category

Dr. Takahiro Pajili

 

Ministry of Health and Welfare Approved Regenerative Medicine Committee, Member of Parliament

Graduated from the University of Tokyo School of Medicine and studied abroad at the University of Pennsylvania School of Medicine in the United States.

Worked at the University of Tokyo Hospital

Medical Advisor, Stem Cell Division, Kohjin Bio Inc.

Book: “The easiest stem cell treatment handbook”

World's first discovery that bone marrow whole stem cell therapy is effective for postherpetic neuralgia

Regularly presents on stem cell therapy at international conferences

paper

Publication of a paper on post-herpetic neuralgia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294184/

It was announced that stem cell therapy for diabetic patients with Alzheimer's disease improved not only the symptoms of diabetes but also the symptoms of Alzheimer's disease. https://onlinelibrary.wiley.com/doi/full/10.1155/2024/8353492

 

Orthopedic Surgery Specialist Graduated from the Faculty of Medicine, University of Tokyo

 

Pediatricians working at Kanto Children's General Hospital

 

Clinical Psychologist Itsuo Esashi

Responsible for: Judging treatment evaluation for ASD, etc.

Work history

National Center for Global Health and Medicine Kokufudai Hospital

Chiba Prefecture Kashiwa Child Guidance Center

Hamamatsu University Hospital, etc.

 

Motor function evaluation for cerebral palsy, etc.

Rehab Tailor Yokohama

 

In the case of pediatric stem cell treatment, a doctor who works (or has worked in the past) at a pediatric general hospital will, in principle, participate.

In addition, in the case of hematopoietic stem cell transplantation, doctors who actually provide treatment at university hospitals such as Keio University Hospital will, in principle, participate.

The participating doctors are participating in the treatment as individuals with a passion for stem cell therapy.

Other doctors who specialize in stem cell treatment are graduates of Keio University, the University of Tokyo, and Hiroshima University School of Medicine.

 

London, Bahrain Department

Professor Ali Ghanem

in embryology and stem cell biology from the University of London.Addressing the molecular regulation of embryonic stem cell (ES stem cell) differentiation. MSc (Honours) in Surgery, University of London; PhD in Embryology and Stem Cell Biology, University of London.

at the University of London School of Medicine and Queen Mary Dentistry.Senior Clinical Lecturer in Plastic and Reconstructive Surgery

Working closely with the world's leading medical experts (Sam Hamra)Facelift, Texas, USA; Nasser Nasser Line OprahMustafa Hamdi Cosmetic Breast Surgery, London, UK;Brussels, Belgium; Fard BenslimaneMicro fat grafting, Casablanca, Morocco; PierpaoloRovatti FaceTiteTM, Verona, Italy,Roger Cooley Regenerative Surgery, Miami, USA)