Shigeru Hasebe
Affiliation
Faculty of Faculty of Pharmaceutical Sciences , Department of Pharmaceutical Sciences
Specialization
Social pharmacy, medical pharmacy, infectious disease treatment, infectious disease epidemiology
keyword
Antibiotic appropriate use, antimicrobial resistance (AMR) countermeasures, HIV infection, real-world data (RWD) analysis
Related Links
profile
Respected Person | Roger Federer |
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Favorite Book | Restart: Leveling Up from Zero (Mighty (Author)) |
Favorite Movies | Doraemon the Movie: Nobita and the Steel Troops |
Childhood Dreams | Driver |
How to spend your holidays | Hiking with kids |
Favorite words | Behomazun |
Risk assessment and pharmaceutical intervention for non-AIDS-related diseases in HIV-infected individuals
In recent years, the prognosis of HIV-infected patients has improved dramatically due to the remarkable progress of anti-HIV drugs. However, on the other hand, it has become clear that the risk of developing so-called non-AIDS-related diseases, such as diabetes, hypertension, dyslipidemia, cardiovascular disease, chronic renal failure, cancer, mental illness, and osteoporosis, is increasing. It is believed that the development of these diseases is complicated by factors such as HIV infection itself, long-term anti-HIV drug use, and polypharmacy, which involves taking multiple drugs simultaneously. Our laboratory aims to evaluate in detail the risk of developing these non-AIDS-related diseases in HIV-infected patients and to elucidate the factors behind them. Through this research, we aim to contribute to the prevention and appropriate management of non-AIDS-related diseases in HIV-infected patients, and to contribute to improving the quality of life (QOL) and extending the healthy lifespan of patients.
A study on the actual situation of appropriate use of antibiotics in community medicine and evaluation of guidelines
In recent years, the increase in drug-resistant bacteria has become a serious global health issue, and the World Health Organization (WHO) predicts that by 2050, the number of annual deaths from drug-resistant bacteria will exceed the number of deaths from cancer. One of the main factors is the inappropriate use of oral antibiotics, which are used on a daily basis. In hospitals, management systems by antibiotic stewardship support teams (AST/ICT) are being established, but the current efforts in community-based pharmacies are not sufficient. Therefore, our laboratory is conducting a detailed investigation of the actual use of antibiotics in community medicine. Through objective analysis based on actual clinical practice, we aim to clarify the issues for promoting the proper use of antibiotics in the community and propose more effective measures. Through this research activity, we hope to suppress the spread of drug-resistant bacteria and contribute to maintaining the health of local residents.