Our surroundings are filled with substances that irritate the skin, such as detergents, cosmetics, and chemicals in the workplace.Irritant contact dermatitisThe number of people suffering from this condition is steadily increasing, and there are many cases where conventional treatments are not effective enough.

Meanwhile, what is attracting attention iscannabinoidIn this article, we will explain the potential of cannabinoids for irritant contact dermatitis from a scientific perspective, based on the latest research results.

What is irritant contact dermatitis?

Basic Understanding

Irritant contact dermatitis is an inflammatory reaction that occurs when chemicals or physical stimuli directly damage the skin. It is different from contact dermatitis that is accompanied by an allergic reaction.Anyone can develop the disease if given enough stimulationin XNUMX minutes by bus from Yonago Station.

Common causative agents include:

• Strong alkaline detergent
• Organic solvent
• Long hours of water work
• UV
• Mechanical friction

Conventional treatments include:Topical steroids,Moisturizerwas the mainstream, but there were issues with side effects from long-term use and large individual differences in effectiveness.

Mechanism of onset

The outermost layer of the skinstratum corneumWhen the lining of the skin is damaged, its barrier function is reduced. This leads to:

1. Decreased water retention
2. Invasion of external stimuli
3. Release of inflammatory mediators
4. Sensitization of nerve endings

This chain reaction occurs, leading to symptoms such as redness, itching, and pain.

What are cannabinoids?

Basic knowledge

What are cannabinoids?Cannabis plantIt is a general term for biologically active substances contained in. The main components are:

• CBD(Cannabidiol): No psychoactive effects
• THC(Tetrahydrocannabinol): Has psychoactive effects

In particular, CBD has been attracting worldwide attention in recent years for its medical value.

Legal status

in Japan,Cannabis Control ActThe use of cannabis containing THC is heavily regulated by the US Food and Drug Administration (FDA). However, CBD:

• Less than 0.3% THC
• Derived from industrial hemp
• Imported as a product

If you meet these conditions, you can use it legally.

Cannabinoids and Dermatitis

scientific basis

A 2023 study found that CBD has the following effects:

• anti-inflammatory
• Neuroprotective effect
• antioxidant effect

Of particular note is that CBDCannabinoid receptors in the skinWhat has been discovered is the pathway that acts on the inflammatory process and suppresses inflammation.

Expected effect

Clinical studies have shown that:

1. Reduction in inflammatory markers: up to 70%
2. Relief of itching: improvement in about 60% of patients
3. Restoration of skin barrier function: Significant improvement in 4 weeks

Practical Information

How To Use

CBD skin care products mainly come in the following forms:

• cream
• oil
• Gel
• ointment

The amount used varies by product, but generally:Twice a dayIt is recommended to apply to clean skin.

How to choose

Quality check points:

1. Inspection and certification by a third partyWith or without
2. CBD content disclosure
3. Indication of origin of raw materials
4. GMP Certification Status

Caution and risks

When using cannabinoid products, it is important to note the following:

• Allergy testingImplementation of
• Consult a doctor (especially if pregnant or breastfeeding)
• Check for interactions with existing medicines
• Small amount test before use

Summary

Cannabinoids, especially CBD, have been shown to be effective against irritant contact dermatitis.New optionsHowever, proper knowledge and caution are required when using it.

Research is expected to continue to develop, but for now:

• Scientific validity
• Few side effects
• Ease of use

So it's an option worth considering.

References and Links

• Ministry of Health, Labor and Welfare eJIM | Cannabis (marijuana) and cannabinoids [supplements, vitamins, minerals - medical professionals]
• Photo by Blocks Fletcher on Unsplash