As a scientist... strong disagree on meta-analyses being on the top of the pyramid. Really well funded, large, statistically rigorous, (if necessary double/blinded and placebo controlled), well designed studies, are the best. Meta-analyses/systematic review are good if you can't get your hands on the former and you are being SUPER CAREFUL about your selection and weighting process.
I dunno man. I found this Youtube channel when I was doing my own resurch, and this one guy... there are so many scientists who refute his claims because he is SO far ahead of them. He's the only science guy I'll listen to from now on.