Sugandhi G

@Book Chapter Varsha Meshram, Khemraj, Pramod Kumar Mahish, Nagendra Kumar Chandrawanshi Mushroom Cultivation and Application in Green Technology In Microbial Approaches for Sustainable Green Technologies Eds. Jata Shankar, Pradeep Verma, Maulin P. Shah CRC Press, Tylor and Francis Group, Boca Raton 2024 Mushroom cultivation is becoming an increasingly promising solution for valorizing agricultural waste in India and the entire globe. Recently mushroom cultivation has been a diverse practice. It is more advantageous than traditional wood tray cultivation, resulting in higher yields and lower contamination rates. Cylindrical baglogs provide better ventilation, which is crucial for the growth of mushrooms, and also allow for easier monitoring of the growing conditions. Spent mushroom substrate (SMS) is a by-product of mushroom production, but various valorization techniques have been developed. SMS can be used as compost, plant-growing media, bioenergy, and biofertilizer. It also allows for the bioconversion of low-value crop waste into high-value protein-rich products, reducing reliance on chemical fertilizers and providing an alternative source of protein. In addition to the environmental benefits, mushroom cultivation can generate employment, making it a promising solution for long-term sustainability in agriculture. In addition, processing enterprises that produce value-added products from mushrooms can create additional income streams for farmers. Adopting new cultivation methods and valorization techniques can further enhance the growth of the mushroom industry. New technologies have been developed to make the cultivation process more efficient and cost-effective. This chapter will focus on the dimension of mushroom cultivation, including an innovative and sustainable practice with improvement for green technology. https://lnkd.in/gkujNAJv

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We are organizing “Hands-on Training on Gene Cloning in Escherichia coli: From Lab to Market” on 30th July 2024 at the Department of Biosciences, Indrashil University, Rajpur, Kadi, Mehsana, Gujarat The training will cover the following aspects: *Basic introduction and applications of gene cloning *Hands-on training on gene cloning *Gene identification, Primer design, PCR for Gene amplification *Qualitative and quantitative of PCR products *Restriction digestion for insert gene and vector preparation and its ligation *Competent cell preparation and transformation *Screening and identification of clone

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I'm thrilled to share our latest research published in Applied Organometallic Chemistry!. A big thank you to my Ph.D. supervisor Prof. Suman Mukhopadhyay, for his valuable support and guidance. This manuscript reports the synthesis and characterization of a series of ruthenium(II)-arene complexes with phenolic acid ligands. Among the synthesized complexes, some display cytotoxicity toward melanoma (A375) cell lines and are non-cytotoxic toward non-cancerous cell lines (HEK 293T). The active complexes induce characteristic apoptotic nuclear changes in the cells, evidenced by a decrease in anti-apoptotic protein (Bcl-xL) expression and an increase in pro-apoptotic protein (PARP) expression, supporting cell death by apoptosis. Developing easy-to-prepare and less toxic metallodrugs as cytotoxic agents is a topic of contemporary interest. In this direction, we explored the potential of ruthenium-arene-phenolic carboxylate complexes as anti-cancer agents.

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Much awaited! ✨ After almost a year in the publication process, my paper 'New Aspects of the Medicinal Value of Cornsilk: A Review' is finally available online in the Natural Products Journal by Bentham Science (IF: 1.2) ✨ The study focuses on corn silk, which has been used for centuries as a natural remedy to treat various medical conditions. Recent research shows the anti-inflammatory effects of corn silk extract, which can help to relieve pain. Certain bio-peptides are involved in the induction of the anti-inflammatory effects of corn silk extract. The analgesic activity of corn silk is due to the presence of tannins and polyphenolic components in Zea mays. In addition to Maysin, many other factors such as steroids, flavonoids, volatile oils and various phenolic oils make cornsilk extract a modern anti-inflammatory and analgesic drug with low side effects. 👩‍🔬 I am grateful to Dr. Sushma Chaturvedi, Professor and HOD, Department of Pharmacology, SGT College of Pharmacy, SGT University for guiding me throughout the publication process as well as Dr. Sonika Shrivastav and Dr. Md. SABIR ALAM. 🙏✨ #publication #cornsilk #research #review #benthamscience

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🔬 Yesterday's lab session delved into the intriguing dynamics between soil bacteria and phytopathogenic fungi. Under the theme 'Highlighting the Antifungal Activity of Bacteria Against Phytopathogenic Fungi,' we embarked on a captivating experiment. Two strains of bacteria, Rhizobacterium and Rhizobium, underwent testing to assess their inhibitory activity on the mycelial growth of phytopathogenic fungi. We selected two representatives from the filamentous fungi family: Aspergillus ochraceus and Fusarium oxysporum. The quest to unveil the antifungal activity of the test bacteria against these phytopathogenic fungi was evaluated using two techniques: the dual-culture method and streaking technique. These methodologies enabled us to visualize and quantify the impact of bacteria on the growth and development of pathogenic fungi. An enriching experience brimming with discoveries and insights, paving the way for new avenues in biological control against plant diseases. #Research #Biology #Agriculture #Microbiology

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Hi everyone! I've just uploaded the 11th lecture of cell biology on my YouTube channel. This lecture covers the fluidity of membrane, function of membrane and membrane transport proteins. I'd love for you all to check it out and share your feedback! ✨ #biotechnology #biotechnologystudent #biotech #microbiology #science #research #genetics #sciencecommunity #lifescience #carrerinbiotech #futureofbiotech #yt #cellbiology #dikshitaramse

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Call for Quality Book Chapters in an Edited Book to Published by Nova Science Publishers TOPICS 1. Introduction to neem plant 2. Overview of neem phytochemistry 3. Azadirachtin and its pharmacological activities 4. Nimbin and related compounds 5. Nimbolide and its pharmacological significance 6. Quercetin and other flavonoids 7. Gedunin and its therapeutic potential 8. Salannin and its biological activities 9. Polysaccharides from neem and their immunomodulatory effects 10. Limonoids and their health benefits 11. Triterpenoids from neem: antimicrobial and antiviral agents 12. Neem bark constituents and oral health 13. Neem leaf extracts: anti-inflammatory and antioxidant agents 14. Neem-based formulations and therapeutic applications Send chapter proposal at ajmergrewal2007@gmail.com

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Nanotechnology Research

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Happy to share my publication," Genomic insights into prevalence of virulence and multi drug resistance genes in milk borne Klebsiella pnuemoniae: Face of emerging resistance to last resort antibiotics" https://lnkd.in/d9dMjgXX

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Scientists at MACS Agharkar Research Institute, Pune, India have identified India's first indigenous methane-eating bacteria, Methylocucumis oryzae, in Western India's rice fields and wetlands. Led by Dr. Monali Rahalkar, the team discovered this novel genus and species of methanotrophs, crucial for mitigating methane emissions—potent greenhouse gases with 26 times the global warming potential of CO2. Named 'methane-eating cucumbers' for their elongated shape, Methylocucumis oryzae shows promising agricultural benefits, promoting early flowering and enhancing grain yield in high-yielding rice varieties. This significant finding, published in the Indian Journal of Microbiology, underscores the role of indigenous microorganisms in combating climate change. Reference 1)https://lnkd.in/g6EJuMPn 2)https://lnkd.in/gEE2Tebt 3) https://rdcu.be/dMUUw #Methylocucumisoryzae #MethaneEatingBacteria #ClimateChange #GreenhouseGas #Microbiology #EnvironmentalScience #ScienceNews #IndiaScience #ResearchDiscovery #WesternGhats #AgharkarResearchInstitute #MicrobialEcology #MitigateMethane #RiceFields #Wetlands #ScienceAndNature

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Biospectrum Organizing Committee is for the first time in Eastern India bringing the opportunity of Synthetic Biology Workshop by iGEM. This workshop is for Undergraduate,Postgraduate students and Research Scholars in hybrid mode. Interested candidates visit www.biospectrum.org #iGEM #syntheticbiology #molecularbiology #CRISPR #BIOTECHNOLOGY #MICROBIOLOGY #GENETICS #PHD #recombinanttechbology #bioinformatics #systemsbiology #metabolicengineering

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We hosted an insightful webinar yesterday by Dr. Nikhil Gandasi, Assistant Professor in Department of Developmental Biology and Genetics at Indian Institute of Science moderated by Dr. Harshavardhan Rao B, Professor at MS Ramaiah Medical College. Dr. Gandasi talked about molecular drivers of diabetes that lead to sub-cellular changes in both young and older people. Here is a recently published work from his lab on Frontiers in Endocrinology, 2024 highlighting the work conducted by his team in diabetes therapy. Link to the paper: https://lnkd.in/gNQRM3r7 Summary: The study revealed that Pheophorbide A, a bioactive chlorophyll breakdown product, modulates the activity of glucose transporters (GLUTs) located in the cell membrane of insulin secreting cells, leading to enhanced glucose uptake by these cells. The binding affinity of Pheophorbide A was found to be comparable with metformin, a conventional medication used to control glucose levels. This suggests that Pheophorbide A could potentially stimulate glucose-induced insulin secretion, which is crucial in managing diabetes. Further studies, conducted using both in-silico (computer-simulated) and in-vitro (lab-based) methods, demonstrated the improved therapeutic potential of the GLUT1-Pheophorbide A complex. These findings are crucial as it could lead to improve management of blood glucose levels in individuals with diabetes.

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Hands-on-Training and strong insight into protein biochemistry techniques at Protein Design Pvt. Ltd. Bengaluru under the valuable guidance of Deepti Saini. #IISC #molecularbiology #internship #protein #elisa #handson #training #biotechnology #biochemistry .

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Immunomodulatory activity of polycaprolactone nanoparticles with calcium phosphate salts against Leishmania infantum infection

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opportunity for PhD graduates

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