GRADE is based on hundreds years of philosophy on how to establish causality and epidemiology method development. There is no problem with “no blinding” or “no RCT”. The only reason “strong evidence from observational studies” is not high quality is it is not strong evidence.
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Erin Reed
@ErinInTheMorn
Everyone: I'm aware of the Cass review. I am carefully reading and formulating my response. There are really good threads out there on its deficiencies already. Until I do, here's an old article that continues to be relevant every time they release these:
erininthemorning.com/p/the-myth-of-
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