7kGnfXXIKZM [Oil, Cancer, Cardiovascular] Dr. Chris Knobbe - 'Diseases of Civilization
https://boards.4chan.org/pol/thread/341148353
PUFA https://boards.4chan.org/pol/thread/344183891

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PUFA Redpills>>>>>>>>

https://www.youtube.com/watch?v=7kGnfXXIKZM [Embed]
https://www.youtube.com/watch?v=sKR1ZdHXXzo [Embed]
https://www.youtube.com/watch?v=rQmqVVmMB3k [Embed]
https://raypeat.com/articles/articles/unsuitablefats.shtml
https://raypeat.com/articles/articles/unsaturatedfats.shtml
https://raypeat.com/articles/articles/unsaturated-oils.shtml
https://raypeat.com/articles/articles/fats-functions-malfunctions.shtml
https://raypeat.com/articles/articles/fishoil.shtml
https://www.jeffnobbs.com/posts/what-causes-chronic-disease
https://www.jeffnobbs.com/posts/death-by-vegetable-oil-what-the-studies-say
https://www.jeffnobbs.com/posts/why-is-vegetable-oil-unhealthy
https://www.jeffnobbs.com/posts/the-environmental-impact-of-vegetable-oils
https://drcate.com/pufa-project/
https://paleoleap.com/many-dangers-of-excess-pufa-consumption/
https://www.alexfergus.com/blog/pufa-s-the-worst-thing-for-your-health-that-you-eat-everyday
https://men-elite.com/2018/06/28/pufa-dangers-part-1-storage-mobilization-and-oxidation/ 
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Pyramid https://boards.4chan.org/pol/thread/348660449
[Weston A. Price] Tooth decay caused by modern diet
https://boards.4chan.org/pol/thread/368699868
[Carnivore] https://www.lainchan.org/r/res/35622.html

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The Carnivore Diet for Brain Health 2023-04-15 17:54:56 No.35622[Watch Thread]

Motivation

Love you, lain.

You all have given me comforting company in some of my most miserable lifetimes, so I think it's only fair of me to make an effort at giving something of substance back.
Many of you apparently suffer from varied mental illness.

I've had at least low-grade depression and compulsions, resulting in escapism and social isolation, for my entire life. Last year, it got particularly bad. I dropped a few letter grades in terms of academic performance, spent my free time daydreaming about somewhere else, and slept for the majority of every day.

I'd tried lots of things to help my mood over the years, so this time, I decided to try something new. On a whim, I decided to try a carnivorous diet, after it was mentioned to me off-hand by a friend. That is, a diet consisting of exclusively ruminant animal meats and fats.

Within a few months, I was completely cured of these lifelong mental conditions. I sleep a normal amount, and don't feel compelled to sleep the day away. My brain works much faster, to the point where caffeine only affects me negatively. I have much more energy throughout the entire day, where before I could only muster up the energy for one activity per day (finish this assignment, work on this programming project, etc.)

I don't believe that my approach may help everybody, or help everybody as drastically, but it helped me very much and it will probably help you too, it's the single best decision I've made in my entire life. As such, I've compiled some thoughts and resources about this way of eating. I do not have the time to prove definitely that it is the best human diet, but I do have the time to give you some food for thought, and answer some common concerns. Concerns are marked in bold.


Mechanisms of Action for Brain Health

"Mental Health" seriously has to be one of the most unfortunate misnomers of the modern era - the diseases contained are not principally mental - they are often more about brain metabolism [1].

The brain, being by far the most energy-hungry organ in the body by mass (consuming some %20 of energy at 3% of weight), is generally sensitive to body metabolic dysfunction. The particular mental illness that results from brain metabolic dysfunction comes down to the areas of greatest weakness in the brain, individually - diseases of excitation paradoxically feel like an excess of energy, but this could be explained by the dysfunction of regulatory structures, like GABA-neurons.

I have mental illness as a result of trauma. Would I benefit from a metabolic intervention like this one?

In my unprofessional opinion, probably at least a little bit. The working scientific theory on trauma posits that its effects in the body are quite physical, including metabolic.
As such, wouldn't it make sense that a metabolic intervention might help?

Here are a few mechanisms of action I've identified for the effects on brain health:

1. Ketosis. Eating exclusively protein and fat will put you into ketosis, a condition of metabolism where your body operates on ketone bodies, produced from fat, instead of glucose. Ketone bodies can supply energy to insulin-resistant cells, where glucose fails. (Insulin resistance is the condition of your body not using glucose very well)

Isn't glucose required for human metabolism?
Yes, a small amount of glucose is required for human metabolism and a few brain structures. However, this amount can be produced by the body itself, endogenously, through the process of gluconeogenesis - producing glucose from proteins.

2. Resolving brain-relevant nutrient deficiencies. Red muscle and organ meat contain high amounts of B vitamins, creatine, iron, and so on. These nutrients are all brain-relevant, if you happen to be deficient, and in more bioavailable forms - consider, for instance, that gluten is technically a protein, and is often marked as such on bread nutritional values. But not all protein is created equal - your body cannot use it effectively. The same is true of plant irons and heme-iron, found in red meat.
Iron, curiously, is also required for the production of dopamine. As such, consuming plenty of bioavailable iron, in my unprofessional opinion, is a good way to treat "dopaminergic addictions", insofar as those actually exist.

3. Reducing toxic load from plants
This is probably going to sound insane to those who aren't aware, but all plants contain chemical defense mechanisms which try to prevent you from faring well if you eat them. This is best explained by [2].

Okay - but aren't ketones an alternative fuel, one that we're not meant to run on all the time? The body preferentially consumes glucose first, before ketones. 
You know what the body likes to consume even before glucose? Alcohol, and its metabolic products, such as acetate. As an aside, this is one of the reasons why alcoholics are the way they are - acetate can also fuel brain cells starved of energy in place of glucose.
The point is - metabolic "preference" may not mean what you think it does. Indeed, the body may consume glucose first so as to keep it down.

Other concerns

Aren't the most long-lived peoples in the world vegetarian, or close to it?
https://www.biorxiv.org/content/10.1101/704080v1
https://www.biorxiv.org/content/10.1101/704080v2

In my opinion, probably not. I would not be surprised if this was propaganda pushed by the world's very wealthy agricultural industries. It would also be very surprising to me that a diet highly inconsistent with human evolution would result in optimal health.

Isn't this way of eating very expensive?
Not necessarily, at least in America. It's certainly far more expensive than cyberpunk soyfood, or beans and rice, but it's a false economy. A diet like that will probably cost you much more in the long run, especially if you require extensive medication, doctor's visits, dentist's visits, and so on.
It's about comparable in price to a standard american diet, containing takeout, junk foods, and the like.
It can also be made cheaper by dealing with farmers directly, if you can manage it.

If I want to switch to this diet, won't I suffer greatly by cutting off the fuel source my body is most accustomed to?
Yes. This is called "keto flu" and is normal - digestive abnormalities may also occur, and are usually temporary.
Over time, these effects (seem to) fade.

What about Vitamin C?
Meat cooked rare contains some vitamin C.
Further, on a diet like this one, your vitamin C requirement will drop substantially. Vitamin C competes with glucose for absorption - no exogenous glucose in the gut, and vitamin c in rare meat is more bioavailable.

What about fiber?
Fiber is not an essential nutrient. It solves some problems caused by carbohydrate, plant-laden diets.

Will I get heart disease from so much fat, and cholesterol?
I encourage you to investigate this question yourself at the bleeding edge of research. The answer is, probably not. [3]

Will I get colon cancer?
As above. The most severe measured effects of red meat (in any study, at all) are far eclipsed by other foodstuffs anyways.


Resources

Here, I dump interesting links and link compilations.


[1]. https://libgen.rs/book/index.php?md5=39EB7B519179642C2AC3025A31DD73B3
[2]. https://yewtu.be/watch?v=j1cqNDDG4aA
[3]. https://yewtu.be/watch?v=rdgS3PuSuyg

https://yewtu.be/watch?v=muAvJ1y64PA
https://yewtu.be/watch?v=BUtwr_6sFw4
https://zerocarbzen.com/
https://justmeat.co/
https://www.mostly-fat.com/
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