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Many of the systematic reviews of evidence for the practice of youth transition are in English. Below is the list of the most notable ones. Not one supports the statement that puberty blockers or hormones are a safe, effective, evidence-based treatment. /8
Germany
Zepf, F. D., König, L., Kaiser, A., Ligges, C., Ligges, M., Roessner, V., Banaschewski, T., & Holtmann, M. (2024). Beyond NICE: Aktualisierte systematische Übersicht zur Evidenzlage der Pubertätsblockade und Hormongabe bei Minderjährigen mit Geschlechtsdysphorie. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 1422-4917/a000972. doi.org/10.1024/1422-4
In English:
econtent.hogrefe.com/doi/suppl/10.1
Sweden
Ludvigsson JF, Adolfsson J, Höistad M, Rydelius PA, Kriström B, Landén M. A systematic review of hormone treatment for children with gender dysphoria and recommendations for research. Acta Paediatrica. 2023;n/a(n/a). doi:10.1111/apa.16791
onlinelibrary.wiley.com/doi/10.1111/ap
UK
National Institute for Health and Care Excellence (NICE). Evidence review: Gonadotrophin releasing hormone analogues for children and adolescents with gender dysphoria. 2020 cass.independent-review.uk/nice-evidence-
National Institute for Health and Care Excellence (NICE). Evidence review: Gender-affirming hormones for children and adolescents with gender dysphoria. 2020. cass.independent-review.uk/nice-evidence-
US
Baker KE, Wilson LM, Sharma R, Dukhanin V, McArthur K, Robinson KA. Hormone Therapy, Mental Health, and Quality of Life Among Transgender People: A Systematic Review. Journal of the Endocrine Society. 2021;5(4):bvab011. doi:10.1210/jendso/bvab011
Canada (overview of systematic reviews)
Brignardello-Peterson R, Wiercioch W. Effects of Gender Affirming Therapies in People with Gender Dysphoria: Evaluation of the Best Available Evidence.; 2022. ahca.myflorida.com/letkidsbekids/
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