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For immunochemical detection of LPA3
Product Categories

Product Type

Antibodies(900)
Polyclonal Antibodies(350)

Research Area

Cell Biology(2,401)
ECM & Adhesion Molecules(57)

Application

Western Blot(766)
Immunocytochemistry(186)
References & Product Citations
Product Description References

1. Chun, J., Goetzl, E.J., Hla, T., et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacological Reviews 54, 265-269 (2002).

2. Fukushima, N., and Chun, J. The LPA receptors. Prostaglandins & Other Lipid Mediators 64, 21-32 (2001).

3. Contos, J.J.A., Ishii, I., and Chun, J. Lysophosphatidic Acid Receptors. Molecular Pharmacology 58, 1188-1196 (2000).

4. Bandoh, K., Aoki, J., Hosono, H., et al. Molecular cloning and characteristics of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. The Journal of Biological Chemisty 274(39), 27776-27785 (1999).

5. Contos, J.J.A., and Chun, J. The mouse lpA3/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern. Gene 267, 243-253 (2001).

Product Citations

Sinderewicz, E., Grycmacher, K., Boruszewska, D., et al. Expression of factors involved in apoptosis and cell survival is correlated with enzymes synthesizing lysophosphatidic acid and its receptors in granulosa cells originating from different types of bovine ovarian follicles. Reprod. Biol. Endocrinol. 15(1), 72 (2017).

LPA3 Polyclonal Antibody

Item No. 10004840
Download Product Insert (PDF)Download Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • EDG-7
  • Lysophosphatidic Acid Receptor 3
Immunogen
Synthetic peptide from the N-terminal region of mouse protein LPA3
Formulation
500 µl of peptide affinity-purified antibody
Storage Buffer
TBS, pH 7.4, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide
Host
Rabbit
Applications
ICC and WB
Species Reactivity
  • (+) Human
  • (+) Mouse
  • (+) Rat
UniProt Accession №
Q9UBY5
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Certificates of Analysis & Batch Specific Data

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

1 ea
$259
Ready to ship
Product Description

Lysophosphatidic acid receptor 3 (LPA3, also known as EDG-7) is one of three LPA receptors (LPA1, LPA2, and LPA3) that are members of large family of G protein-coupled receptors that also include those for sphingosine-1-phosphate (S1P1-5).1 The LPA receptors mediate many cellular responses including cytoskeletal rearrangements, cell proliferation, and inhibition of gap junction communication.2,3 Mouse and human LPA3 have 353 amino acids with an estimated molecular weight of 40 kDa.4,5 The mRNA level of LPA3 is high in testes, kidney, and lung but low in intestine, heart, thymus, and stomach.5 Cayman Chemical’s LPA3 polyclonal antibody can be used for western blot and immunocytochemical analysis for LPA3 on samples of human, mouse, and rat origin. Cayman’s LPA3 Polyclonal Antibody detects a protein at around 40 kDa in human HepG2 cells, mouse macrophages, and in mouse and rat liver.

WARNING This product is not for human or veterinary use.

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