Contents
Vol 6, Issue 266
Contents
Research Articles
- Signaling by p38 MAPK Stimulates Nuclear Localization of the Microprocessor Component p68 for Processing of Selected Primary MicroRNAs
An early step in microRNA processing depends on signaling downstream of the p38 mitogen-activated protein kinase.
- Cell-to-Cell Variability Analysis Dissects the Plasticity of Signaling of Common γ Chain Cytokines in T Cells
Sequestration of signaling subunits by IL-2 receptors inhibits IL-7 responsiveness in T cells.
Meeting Report
- The Emergence of the Conserved AAA+ ATPases Pontin and Reptin on the Signaling Landscape
The AAA+ ATPases Pontin and Reptin play a diverse role in cell biology and signaling.
Podcast
- Science Signaling Podcast: 12 March 2013
Variability in receptor protein abundance affects the sensitivity of T cells to the cytokines IL-2 and IL-7.
Editors' Choice
- Glial Death Star
The lipocalin lcn2 is secreted from reactive astrocytes and induces neuronal cell death.
- Old Drug, New Purpose for Obesity
An anti-inflammatory drug reverses disease phenotypes in obese mice by inhibiting noncanonical inflammatory mediators in liver and fat cells.
- VEGFR Internalization Promotes Sprouting
Vascular endothelial growth factor receptor is stable at the surface of center vessels and rapidly endocytosed, degraded, and synthesized at sites of endothelial sprouting.
- Bees Get That Caffeine "Buzz"
Caffeine at concentrations found in flowers helps individual honeybees remember where to find associated nectar.
' stroke='#fff' stroke-width='2' fill='none' fill-rule='evenodd'><circle fill-opacity='.8' fill='#000' cx='10' cy='10' r='10'/><g stroke-linecap='square'><path d='M5.5 5.5l9 9M14.5 5.5l-9 9'/></g></g></svg>){kind=small}