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Stay calm and focused by learning to control your body's natural stress response.

Stay calm and focused by learning to control your body's natural stress response. Read more
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Lief Therapeutics
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Lief Therapeutics

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About this project

 

Stress is a part of modern life, but its long-term effect on our health and productivity can be dramatic. Chronic stress can literally kill you, increasing your risk for heart attack and stroke by up to 50%.

Lief tracks and optimizes your resiliency to stress by increasing your natural heart rate variability (HRV), a biomarker of your physical and psychological health. A low HRV score is linked with anxiety, distraction and poor performance - things we'd all prefer to avoid.

The good news is, you can improve your HRV and train yourself to stay focused and in control throughout your day. The device's scientifically-validated HRV biofeedback exercises have been used by doctors, psychologists and coaches for decades. It's safe, drug-free and has improved stress, mood and focus for thousands of people.

 

 

 

 

 

The shape of the Lief is designed to comfortably fit and bend with your torso. The patch is just 6mm thin and sits under your clothing discreetly. Lief uses stickers for all-day wear without restrictive straps.

 

Put Lief on in the morning, then forget about it. When your body needs a reset or it’s time to train, Lief's quiet vibrations make sure you're the only one that notices. You don't need a screen to understand what's going on, or what to do next. Just notice the vibration and follow along with your breath.

  

Lief uses short 3-minute biofeedback exercises or “doses” as a central training tool in building long-term results. By practicing throughout the day, you can maintain your physical and emotional resiliency while staying focused and balanced.

 

 

 

 

Developed with Stanford and UCSF clinicians, the Lief support app helps you record your thoughts, emotions, behaviors, and sensations. The app combines with Lief to uncover and untangle thinking patterns that are negatively affecting your body. 

  • Thought Records 
  • Progress reviews 
  • Self-regulation toolkit 
  • Audio exercises 
  • Mood rating


Simply follow the in-app instructions, choose your training schedule and start. It’s that simple.

 

 

The Lief measures your heart rate variability (HRV) to recognize your stress patterns with clinical-grade accuracy. HRV is the healthy variation in your heart rate, and it can act as a robust biomarker of stress and psychological health.

High HRV is generally highly desirable, indicating a calm, focused state. Extremely low HRV, by contrast, is a clue something may be off with your autonomic nervous system.

When your mind and body are relaxed, your heart naturally speeds up on each inhale, and slows down on each exhale. This creates high HRV, and a gentle wave pattern in your heart rate known as respiratory sinus arrhythmia. 

The Lief allows you to improve your HRV by breathing with your heart's intrinsic rhythm. This resonant breathing exercise, known as HRV biofeedback, is a simple and safe way to amplify your HRV wave.

Listen to a brief explanation of HRV and the benefits of HRV biofeedback from a pioneer in the field, Dr. Richard Gevirtz, Ph.D.

 You can learn more about HRV and HRV biofeedback here.

  

 

Lief’s journey began in Harvard and Stanford neuroscience labs studying meditation’s effect on the human brain. After discovering first-hand that meditation techniques truly did have a positive impact on people’s health and wellbeing, we spent nearly a year trekking through the Himalayan mountains to measure the brainwaves and heartbeats of meditating Tibetan monks.

The journey was profound, discovering first-hand the power a trained mind can have over the body, and how deeply the heart is connected to our minds. These masters demonstrated their ability to change the temperature of their body, speed up and slow down their heart at will, and perhaps most profound was their clarity and empathy.

Eventually we returned to San Francisco to use our personal, scientific, and data learnings to turn over a new "Lief" and build the product we have today.

 

 

 

 

 

Our team went through dozens of prototypes, from a bulky chest strap vibrating to our heart beat to our final sleek patch form factor. Much of our exploration has been guided by these design goals:

  • Maintain highest signal quality to give true insight 
  • Develop the right form factor, comfortable, flexible 
  • Finding an interaction modality that's discreet without "broadcasting"
  • Develop a training methodology that works in daily life, without sacrificing signal quality and experience.

 

 

 

 

 

 

Risks and challenges

We’ve worked for years to bring you Lief, iterating through dozens of prototypes and manufacturing techniques. Today Liefs are being locally manufactured, tested and shipped to our early beta users in the San Francisco bay area.

But even with lots of early user feedback and great manufacturing mentors (thank you Hax and ZeroDiff) building hardware is hard. We want to be clear about the major remaining risks to shipping on time: our flexible design and creating production tooling.

Most electronic products are encased in hard plastic shells to protect their components. The Lief is packed with sophisticated electronics, but has the added design challenge of flexing to fit your body. We’ve come up with some innovative techniques to ensure manufacturability of a product as unique as the Lief, but it’s possible that we will still need to tweak our processes on the factory floor. We are mitigating this risk to the schedule proactively by engineering reliability testing at multiple points to catch errors quickly.

All our prototypes were initially made with plastic molds. To make devices at larger quantities, we are designing a production steel mold or “tool” with the help our manufacturing partner. It’s possible that this process may require one or multiple re-designs of our tool. Delays with the factory can add days to the timeline. Days can become weeks. To mitigate this risk, our technical team will be on-site at the factory during critical periods. Additionally, we have built an extra buffer into our production schedule to account for most reasonable setbacks. We feel confident you'll receive your Lief on time and we'll continue to be transparent and timely in our communication and manufacturing updates.

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FAQ

  • The Pro device is for the data lovers out there. The Pro can sync your data to a web dashboard where you can analyze, graph and export your data into other 3rd party programs.

    Your Pro also comes with more memory (128 MB vs 64 MB) so it can record without syncing to the app for up to a month. Never lose your data!

    Last updated:
  • Wrist-worn heart rate monitors can give you average heart rate over a period of time, but to calculate HRV you need millisecond timing accuracy from heartbeat to heartbeat.

    The Lief uses the electrocardiogram or ECG signal, the medical gold standard sensor for HRV measurement. ECG is simply the only way to accurately and reliably calculate your HRV. In addition, Lief is placed close to your the heart which increases signal strength significantly.

    See this white paper on accuracy differences between the Fitbit Surge and medical ECG sensors: http://getlief.com/static/papers/Fitbit_Validation_Study.pdf

    Last updated:
  • You can wear the Lief at night to record your HRV, heart rate, breathing and movement while you sleep. There is strong evidence that low HRV during the day can lead to poor sleep quality at night. You can track and optimize your sleep quality with the Lief's day-time and night-time data.

    Lief does not explicitly analyze your sleep stages and quality, but all your data is available to you in the app (and with the Pro, exportable to 3rd party programs for deeper analysis.) Optionally, wear your Lief in airplane mode to turn off the Bluetooth radio, then sync with your phone when you wake up the next day.

    Last updated:
  • This is a common question. Most wellness-focused wearables out there alert you when you're stressed. There's no clear next step to take, so the tension can be compounded.

    The Lief is different - it doesn't just monitor your stress, it's a real-time, in-the-moment exercise that makes you feel better, even when you're not feeling your best.

    Last updated:
  • Lief uses standard ECG stickers so you can use any of dozens of cheap, easily available brands. Searching for "ECG electrodes" on Amazon brings up results in the 20-30 cent per sticker range, and you can save by buying in bulk.

    We tested dozens of different stickers, and the daily use brand included with your Lief were the preferred choice of our pilot users. While we will supply these skin-safe, medical-grade stickers to you as an ongoing convenience service, most standard “ECG electrodes” on Amazon work with Lief and you are not locked in to us.

    We're currently working with Somaxis, a bio-monitoring device company, to create what we feel is "the perfect sticker" for all day use. These will be offered as soon as they become available as an additional option and similar price point to existing brands.

    Last updated:
  • Lief uses standard medical ECG stickers, and there are dozens of major brands for every skin type and use case. The stickers we ship with your Lief are recommended for daily use, but other ECG stickers easily available on Amazon, and can last up to week.

    A big part of the answer to this question is, it depends on your own preferences and skin type. For people with very sensitive skin, we recommend pediatric stickers that you throw away daily.

    Last updated:
  • Yes. Your Lief can be placed in Airplane Mode, which means the radio will remain turned off and all data will simply be stored to local flash. When you have a need to connect to your app or sync data, just hit the Lief's button three times to turn Airplane Mode off.

    Lief retains its core functionality independently of your phone or a Bluetooth connection, so you can reduce your total EMF exposure and still gain most of the utility of the patch.

    Last updated:
  • The Lief runs on a lithium polymer battery, which typically supports 300-400 charges over the course of its life. In monitoring mode, your Lief can last up to a week without charging, so we estimate the Lief's battery will last 3-5 years with normal use.

    Last updated:
  • Yes, the Lief companion app will support both Apple and Android devices. Windows phones and other smartphones are not currently supported.

    Last updated:

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    Pledge $5 or more About $5

    Thank you!

    Lend us your support in bringing this product to life! We'll keep you updated with news, learnings, and beta opportunities as you help make this product a reality.

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    Self-Regulation Toolkit

    Receive a digital 8 week mini-course from leaders in the fields of psychology, biofeedback, mindfulness and behavior design. Listen in as these experts explain the science and techniques Lief uses in a simple and practical way. You might not have a Lief patch, but we'll guide you in training with your heartbeat (which is always accessible), and include audio practices to build your self-regulation skills over 8 weeks and beyond.

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    Pledge $159 or more About $159

    SUPER Early Bird - Lief Smart

    Be the first to own the Lief! As a passionate supporter, we want to give you the biggest discount possible.

    (Save 47%!!! - retail price $299)

    Includes
    • Lief Smart Patch
    • 1 microUSB charger
    • 8 weeks of Lief stickers
    • Lief App and Self-Regulation Toolkit
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    Early Bird - Lief Smart

    Be one of the first to own the Lief!

    (Save 40%!!! - retail price $299)

    Includes
    • Lief Smart Patch
    • 1 microUSB charger
    • 8 weeks of Lief stickers
    • Lief App and Self-Regulation Toolkit
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    Lief Smart

    Be one of the first to own the Lief!

    (Save 33% - retail price $299)

    Includes
    • Lief Smart Patch
    • 1 microUSB charger
    • 8 weeks of Lief stickers
    • Lief App and Self-Regulation Toolkit
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    Early Bird - Lief Pro

    Be the first to get the most accurate and actionable continuous HRV monitor on the market. This model includes 1 month of on-board data storage and unlimited data export.

    (Save 37% - retail price $399)

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    Pledge $269 or more About $269

    Lief Pro

    Be the first to get one of the most accurate and accessible continuous HRV monitors on the market. This model includes 1 month of on-board data storage and unlimited data export.

    (Save 33% - retail price $399)

    Includes
    • Lief Pro Patch
    • 1 microUSB charger
    • 8 weeks of Lief stickers
    • Lief App and Self-Regulation Toolkit
    • R-R intervals export option
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    Lief Buddy Pack

    Get the Lief, and share it with a partner or friend. Practice together, and hold each other accountable to make lasting change.

    (Save 40% - retail price $598)

    Includes
    • Lief Smart Patch (x2)
    • 1 microUSB charger (x2)
    • 8 weeks of Lief stickers (x2)
    • Lief App and Self-Regulation Toolkit (x2)
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    Pledge $1,395 or more About $1,395

    5 Lief Pros

    Get 5 Lief Pro's and a web dashboard to easily view the data of all your connected users, and export the R-R intervals to analyze.

    (Save 30% - retail price $1,995)

    Includes
    • Lief Pro Patch (x5)
    • 1 microUSB charger (x5)
    • 8 weeks of Lief stickers (x5)
    • Lief App and Self-Regulation Toolkit (x5)
    • R-R intervals export option (x5)
    • Web Dashboard (x5)
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    Pledge $2,690 or more About $2,690

    10 Lief Pros

    Get 10 Lief Pro's, and have a personalized video workshop led by the Lief founders just for you! This includes a web dashboard to easily view the data of all your connected users, and export the R-R intervals to analyze.

    (Save 33% - retail price $3,990)

    Includes
    • Lief Patch (x10)
    • 1 microUSB charger (x10)
    • 8 weeks of Lief stickers (x10)
    • Lief App and Self-Regulation Toolkit (x10)
    • R-R intervals export option (x10)
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