Launching perhaps her most loaded charge yet at Donald Trump, Hillary Clinton painted a picture of the Republican nominee as a dangerous candidate who has granted the GOP’s “radical fringe” a powerful voice with his campaign rhetoric.

“From the start, Donald Trump has built his campaign on prejudice and paranoia,” Clinton said on Thursday at a speech in Nevada. “He’s taking hate groups mainstream and helping a radical fringe take over one of America’s two major political parties.”

Story Continued Below

She called him “profoundly dangerous.”

“A man with a long history of racial discrimination, who traffics in dark conspiracy theories drawn from the pages of supermarket tabloids and the far reaches of the internet, should never run our government or command our military,” she said.

With Trump working hard in recent days to appeal to African-American voters, Clinton hammered the appeals the Manhattan billionaire has offered to the black community. She said Trump “misses so much” in making his case to black voters, including the “vibrancy” of black-owned businesses, the “excellence” of historically black colleges and universities and the “pride” of African-Americans watching their children thrive.

She also recalled the lawsuit filed against Trump that accused him of refusing to rent to black and Hispanic tenants. She said his first foray into the political world, his spearheading of the so-called “birther” movement that questioned whether President Barack Obama had been born in the United States, amounted to an effort to “delegitimize America’s first black President.”

“It takes a lot of nerve to ask people he’s ignored and mistreated for decades, ‘what do you have to lose?’” Clinton said, repeating a question Trump has asked of black voters before the mostly white audiences at his rallies. “Because the answer is everything.”

With Trump tacking quickly away from the hardline immigration stance upon which he built his campaign, Clinton recalled the Trump Tower speech he delivered on the day he launched his White House bid in which he said of Mexican immigrants, “They’re bringing drugs, they’re bringing crime, they’re rapists, and some, I assume, are good people.”

“Since then, there’s been a steady stream of bigotry,” she said.

From there, Clinton listed the litany of controversies that have swirled around Trump’s campaign. She pointed to his initial refusal to repudiate an endorsement from former Ku Klux Klan leader David Duke and his decision to retweet a message from an anti-Semitic Twitter account. She asked the crowd to “think about” what it meant that the Republican nominee for president accused a Hispanic federal judge of being biased against him because of his heritage.

The former secretary of state also attacked Trump’s penchant for “pushing discredited conspiracy theories with racist undertones.” She cited Trump’s debunked statement that he had seen Muslims in New Jersey celebrating the Sept. 11 terrorist attacks as well as the reality TV star’s suggestion, without evidence, that Sen. Ted Cruz’s father was somehow involved in the assassination of President John F. Kennedy. Pulling an example from the general election, she raised how Trump had accused President Obama of founding the Islamic State militant group and then “repeated that nonsense over and over.”

“This is what happens when you treat the National Enquirer like Gospel,” she said. “The last thing we need in the Situation Room is a loose cannon who can’t tell the difference between fact and fiction, and who buys so easily into racially-tinged rumors.”

Clinton refused to let Trump easily back away from another of his Republican primary proposals, to institute a temporary ban on all Muslims entering the United States. The Manhattan billionaire has backed away from that plan in recent weeks, instead favoring a policy of temporarily banning individuals from certain countries from entering the U.S.

Firmly pinning the first proposal to ban all Muslims to her GOP opponent, Clinton asked how such a policy would even work. She pondered aloud what would happen at U.S. customs and border protection stations in American airports, where agents would be forced to ask foreign travelers what faith they practice. “What if someone says, 'I’m a Christian,' but the agent doesn’t believe them?” Clinton wondered. “Do they have to prove it? How would they do that?”

Such a policy would make the U.S. the only nation in the world with a religious test for entry, Clinton said. The only other place that institutes such a test, the former secretary of state said, is the territory controlled by the Islamic State.

“It would be a cruel irony if America followed its lead,” she said.

Clinton called out Trump’s decision to bring on Breitbart executive Stephen Bannon to be his campaign CEO, saying Breitbart’s reputation for engaging in “Alt-Right” philosophies matches with the Trump campaign.

“A fringe element has effectively taken over the Republican Party,” Clinton said. “All of this adds up to something we’ve never seen before. Of course there’s always been a paranoid fringe in our politics, steeped in racial resentment. But it’s never had the nominee of a major party stoking it, encouraging it, and giving it a national megaphone. Until now.”

She pointed to Breitbart headlines like "Birth Control Makes Women Unattractive and Crazy," “Would You Rather Your Child Had Feminism or Cancer?” and “Gabby Giffords: The Gun Control Movement’s Human Shield” as evidence that the website once run by Bannon is out of step with the American public.

“Just imagine,” Clinton said. “Donald Trump reading that and thinking: ‘This is what I need more of in my campaign.’”

She said Bannon’s hiring makes sense, since Trump is “the only Presidential candidate ever to get into a public feud with the Pope.”

Trump denounced Clinton’s accusations at a New Hampshire rally Thursday afternoon, which were also starkly presented in a video released by the campaign that includes images of the KKK and other white supremacists. The video quotes an unnamed KKK imperial wizard saying "the reason a lot of Klan members like Donald Trump is because a lot of what he believes, we believe in." It labels the "Alt-Right" movement as "the sort of dressed-up-in-suits version of the neo-Nazi and white supremacist movements.”

"Now, I've not seen what Hillary is going to say, but I've heard about it. And, in a sense, I don’t want to dignify her statements by dwelling on them too much, but a response is required for the sake of all decent voters that she is trying to smear," Trump said.

"She lies and she smears and she paints decent Americans — you — as racists," Trump continued. "She bullies voters who only want a better future, and tries to intimidate them out of voting for a change. I'm for change. She doesn't want change."

Even before Trump took the stage in New Hampshire, his campaign denounced Clinton's video with a statement from Mark Burns, an Evangelical pastor and campaign surrogate, who said the video was a "disgusting new low" for the former secretary of state.

"Hillary Clinton and her campaign went to a disgusting new low today as they released a video tying the Trump Campaign with horrific racial images,” pastor Mark Burns said in a statement emailed out Thursday by the Trump campaign. “This type of rhetoric and repulsive advertising is revolting and completely beyond the pale. I call on Hillary Clinton to disavow this video and her campaign for this sickening act that has no place in our world."