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Landmark Study Shows Antidepressants No More Effective than Placebo (thelastamericanvagabond.com)

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[–]Elzendobob 7ポイント8ポイント  (21子コメント)

Thanks for heaping even more of a negative stigma on people that need and use these drugs to stay in the normal zone.

[–]Amos_Quito 2ポイント3ポイント  (5子コメント)

Thanks for heaping even more of a negative stigma on people that need and use these drugs to stay in the normal zone.

Take the placebo. There's a good chance that it will perform as well, but without all the side-effects.

Challenging Received Wisdom: Antidepressants and the Placebo Effect

Edited: A word - Take

[–]Elzendobob 2ポイント3ポイント  (4子コメント)

It's great for the undiagnosed to pass judgement

[–]Amos_Quito [スコア非表示]  (0子コメント)

Hey, you do what you feel is best for YOU. Consult with your doctors, and, after careful consideration, follow the path that suits you best.

But I would urge you to recall that you must be your own advocate, for at the end of the day, it is you, not me, and not your doctors, who will have to live with the consequences.

In your own interest, please do consider reading the following:

Challenging Received Wisdom: Antidepressants and the Placebo Effect

Also, you may wish to take a moment to learn more about any medication you've been prescribed, and others' experiences.

www.askapatient.com

Wishing you all the best.

[–]TheStrangeTamer -2ポイント-1ポイント  (2子コメント)

wait and see what these pills end up doing.. End of life is going to be torturous for all of these users. the Brain Damage is real.

[–]FDFGate1989 -1ポイント0ポイント  (12子コメント)

There aren't as many of those people as you think. Doctors should be recommending improving your diet, working proper amounts of physical activity into your schedule, and 8+ hours of sleep. Unfortunately, there's too many people who want a bandaid rather than actually fixing their problems.

[–]Elzendobob 6ポイント7ポイント  (1子コメント)

Oh come on...bi polar disorder and major depression require medications and no amount of good nutrition and sleep change that.Why persecute people that need medication by telling them they don't need medication.It is so condescending and dismissive of so much science and knowledge.

[–]malicious_turtle 1ポイント2ポイント  (0子コメント)

The person you're replying to is right...in a way. Doctors are too quick to just go prescribing anti depressants to people who only have very mild symptoms of depression. A 2 week camping trip to the Rockies or Alps or something would go a lot further to curing them than any pill. Obviously someone who has depression that isn't caused by their environment or a high stress lifestyle won't show any improvement without medical assistance.

[–]minecraft_ece 0ポイント1ポイント  (5子コメント)

Unfortunately, those recommendations are incompatible with current american lifestyle of work first work always work work work. Bandaids and shortcuts are all most americans can afford.

[–]FDFGate1989 -2ポイント-1ポイント  (4子コメント)

Sounds like laziness. If you actually try you can work some rice, vegetables, and sleep into your schedule.

[–]minecraft_ece 1ポイント2ポイント  (0子コメント)

I'm too busy pulling myself up by my own bootstraps to do any of that.

[–]Frontfart 0ポイント1ポイント  (2子コメント)

Rice? If I eat rice I can almost see the fat accumulating.

[–]FDFGate1989 0ポイント1ポイント  (1子コメント)

To become a fat fuck you need to eat like one.

[–]TheStrangeTamer -1ポイント0ポイント  (2子コメント)

Most grocery stores do not have healthy options and people love to be stuck in their ruts "Fast Food Nation".. a few changes to their diets and cooking and body care items.. All without bullshit medications and people can change. But most of the problem is the food and the endocrine disrupters screwing up their hormones

[–]Ihateverything94 2ポイント3ポイント  (0子コメント)

there was mental illness before fast food came about
not saying that cant play a part though

[–]FDFGate1989 1ポイント2ポイント  (0子コメント)

Most grocery stores do not have healthy options

Really? I am pretty sure to be a grocery store you have to have those options. Otherwise you could just be a Walgreens or a CVS.

[–]TheStrangeTamer -3ポイント-2ポイント  (1子コメント)

Dont be dumb

[–]Elzendobob 2ポイント3ポイント  (0子コメント)

I know lots of folks that benefit from antidepressant medication.

[–]tiagoratto 8ポイント9ポイント  (1子コメント)

Says the guys who never took them

[–]DrDougExeter 1ポイント2ポイント  (0子コメント)

I've taken them. They never did jack shit for me except give awful side effects.

[–]NutriaSystem 5ポイント6ポイント  (2子コメント)

(Note the study only addressed children and teenaged patients.)

[–]Amos_Quito 2ポイント3ポイント  (1子コメント)

(Note the study only addressed children and teenaged patients.)

THIS study, yes, but it had previously been established that the results is virtually the same among adults:

PLOS Medicine - February, 2008

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

Abstract

Background

Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, the benefit falls below accepted criteria for clinical significance. Yet, the efficacy of the antidepressants may also depend on the severity of initial depression scores. The purpose of this analysis is to establish the relation of baseline severity and antidepressant efficacy using a relevant dataset of published and unpublished clinical trials.

[...]

Conclusions

Drug–placebo differences in antidepressant efficacy increase as a function of baseline severity, but are relatively small even for severely depressed patients. The relationship between initial severity and antidepressant efficacy is attributable to decreased responsiveness to placebo among very severely depressed patients, rather than to increased responsiveness to medication.

[–]blackheartblackmask 1ポイント2ポイント  (0子コメント)

So not only does it not work it makes it worse. Pretty much what I suspected.

[–]Frontfart 1ポイント2ポイント  (0子コメント)

So when I went from wanting to kill myself and stay in bed to thinking rationally and not having overwhelming guilt and shame and even being able to laugh again, that was all in my head?

Bullshit.

[–]Amos_Quito 2ポイント3ポイント  (5子コメント)

Link to the Lancet page:

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30385-3/abstract

EDIT: While the drugs may not have relieved depression, they did offer something that the placebos did not: Nasty side-effects.

[–]brownestrabbit 1ポイント2ポイント  (0子コメント)

You forgot the best side effect of all: massive profits*

* limited access to massive profits may apply

[–]aethelberga -1ポイント0ポイント  (3子コメント)

I was going to ask, were their side effects no worse than a placebo either? Probably not.

[–]Amos_Quito 1ポイント2ポイント  (0子コメント)

While the efficacy of the AD's listed may be questionable, their negative side-effects, unfortunately, are well established.

[–]lucycohen 1ポイント2ポイント  (1子コメント)

Suicide is a side effect of these pills

[–]flyyyyyyyyy 1ポイント2ポイント  (3子コメント)

well they kill your dick and give you the shits, so there's that.

[–]Frontfart 2ポイント3ポイント  (0子コメント)

Actually I got my sex drive back.

[–]brownestrabbit 0ポイント1ポイント  (1子コメント)

Those are only symptoms typical of a transition phase from human to zombie. It's completely normal and nothing to be concerned with.

[–]lucycohen 0ポイント1ポイント  (0子コメント)

They sure make good money though

[–]brownestrabbit -1ポイント0ポイント  (1子コメント)

Fuck all the shills that question the effectiveness of holistic approaches that encourage better living, healthier eating, and are far less risky than drugs like these.

Fuck all the dipshits that quote this snarky asshole:

“You know what they call alternative medicine that's been proved to work? - Medicine.”

― Tim Minchin

[–]dsfkjsd -1ポイント0ポイント  (0子コメント)

I have tried them all.. Only way they are considered effective is they make you feel more comfortable with eating a bullet. Pure poison.

[–]stalker437 -1ポイント0ポイント  (2子コメント)

I've tried all and none of them have worked

[–]omenofdread -1ポイント0ポイント  (0子コメント)

a blunt works though... guess that's why its illegal.

[–]ekelarc -1ポイント0ポイント  (0子コメント)

Suicide mass murder pills that's the sponsor oh gotta shut that down can't have that why is suicide the leading cause of death I'm trying to save people you're a hatchet man of the new world order I'm tired of the same old stuff here pal

[–]TheStrangeTamer -2ポイント-1ポイント  (0子コメント)

True they DO Absolutely nothing for your depression you are being treated for.. But just try and stop and see what Hell you go through.. LOL you thought you were depressed before you started.. Stop and see..

Chemical imbalances are bullshit.. and treating depression with a pill is even more insane