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Pills Dissolving Time-Lapse (gfycat.com)

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[–]Karthinator 135ポイント136ポイント  (4子コメント)

That is surprisingly disgusting. They look like lysing bacteria. I love it.

[–]Broken_Kerning 10ポイント11ポイント  (3子コメント)

My chemical engineering problem sets lied to me. They were hard enough given all their simplifying assumptions! I wonder how pharmaceutical engineers model this dissolution.

[–]Karthinator 11ポイント12ポイント  (0子コメント)

I doubt real world modeling is done as manually as your problem sets, given that the point for you is to be taught at vs actually figuring something unknown out. That said, they probably use different models entirely if at all.

[–]littlesweatervest 4ポイント5ポイント  (0子コメント)

Well if you're looking for the time it takes to dissolve, then it wouldn't be too hard. Weigh 10 pills dry and put them in acid that would simulate the stomach. Each pill would dissolve for a specific time. 1 minute, 2 minutes, 5 min, 10 and so on. After the spcified time we filter out the remaining solid and quickly dry it. Weigh again, plot it vs time and determine the relationship (linear, parabolic, etc). We could repeat with a powder too. You would then be able to determine the respective dissolution rates of the pills powder and the encapsulating layer.

[–]UmiNotsuki 0ポイント1ポイント  (0子コメント)

Taken a few classes on this, though I'm no expert by any means. The basic gist of it is that you can use empirical relationships between drug release fraction and time for a given material and just stack your layers on top of one another mathematically. No one really cares that, for instance, 80% of the drug is released on one side in a quick burst, only that there's a quick spike in the release, These things are usually small enough that diffusion is assumed to take care of the gradient across the area of the pill.

[–]Real_Clever_Username 46ポイント47ポイント  (3子コメント)

The last one was the best

[–]BroadStreet_Bully5 39ポイント40ポイント  (1子コメント)

I think it was a time release, that's why it didn't just explode like the others.

[–]theghostmachine 4ポイント5ポイント  (0子コメント)

Ah, thanks. I just posted asking if that was time-release.

[–]nider 36ポイント37ポイント  (15子コメント)

Its amazing how a little tiny amount of something could change your body and mind.

[–]InactiveBeef 11ポイント12ポイント  (0子コメント)

This video is a little longer and shows other pills being dissolved.

[–]TOASTuh[S] 11ポイント12ポイント  (2子コメント)

Source

[–]wadech 1ポイント2ポイント  (1子コメント)

I'm curious what the actual elapsed time was for those.

[–]polynomialpusher 1ポイント2ポイント  (0子コメント)

They took significantly different amounts of time to dissolve. The red one dissolved within a minute, so I had to take photos as fast as I could. The green Excedrin took forever to fully open. To be fair, tap water is a poor substitute for stomach acid.

[–]aFuzzySponge 10ポイント11ポイント  (7子コメント)

What are they dissolving in? Water?

[–]TOASTuh[S] 14ポイント15ポイント  (6子コメント)

Tap water

[–]lightheat 27ポイント28ポイント  (5子コメント)

I'd be interested in seeing what they look like dissolving in something like HCl, something closer to stomach acids.

[–]reckford 22ポイント23ポイント  (3子コメント)

it would likely look the same. Acid really only changes the ionization states of the drug molecules and anything that would be susceptible to degradation under those conditions has special coatings (like enteric coated aspirin) or excipients to prevent any damage from happening.

[–]lightheat 9ポイント10ポイント  (2子コメント)

Neat! Thanks.

[–]xX420shREKTm8Caesium + Fluorine 1ポイント2ポイント  (1子コメント)

Perhaps you were wondering about other liquids things can be dissolved in (I know there is a word for it but I don't want to spell it and look like an idiot) like ethanol or ether. If you were, I would be very interested as well!

[–]RockTheMouse 3ポイント4ポイント  (0子コメント)

I worked in a lab that actually had an instrument that mimicked a stomach, it was a more acidic solution and there was some mechanic that slowly jostled the liquid as if a person were moving around. Pretty cool stuff.

[–]samprog 24ポイント25ポイント  (0子コメント)

It's really sad to watch these pills die #allpillsmatter

[–]SubliminalPepper 5ポイント6ポイント  (0子コメント)

That last pill looked like it had a solar flare

[–]blindreefer 3ポイント4ポイント  (0子コメント)

Reminds me of Requiem for a Dream

[–]aega100 1ポイント2ポイント  (0子コメント)

Someone should reverste those!

[–]CensoryDeprivation 2ポイント3ポイント  (0子コメント)

mmmm delicious drug filling

[–]Madmartigan1 3ポイント4ポイント  (0子コメント)

Zantac. I'd bet my life on it.

[–]Lunchables 2ポイント3ポイント  (1子コメント)

Can someone please animate this an upload to /r/reallifedoodles? :)

[–]OptimalCynic 1ポイント2ポイント  (0子コメント)

The first one already has the eyeballs.

[–]joshuad80 2ポイント3ポイント  (0子コメント)

The blue E pill was my favorite.

The last one was my least favorite.

[–]yohney 7ポイント8ポイント  (0子コメント)

I misread the title as "piss disolving time-lapse".

At first I was like wtf. But, curious, I nonetheless opened and was confused. Reread the title. Disappointment.

But such is life.

[–]darthmarth 1ポイント2ポイント  (0子コメント)

/r/mildlyinteresting

[–]EKHawkman 2ポイント3ポイント  (0子コメント)

The one thing I'd like to see here is how mechanical disturbances change the dissolving process. More like how the body works.

[–]bmichel 1ポイント2ポイント  (1子コメント)

So, the question I have is, are pills 'designed' in a certain way to release or expose different parts of themselves are a certain time?

Is there structure in the way they are put together?

[–]Squishy90 1ポイント2ポイント  (0子コメント)

Some do, yes. This article explains it all, it's really cool! https://en.wikipedia.org/wiki/Time_release_technology

[–]3xt 1ポイント2ポイント  (0子コメント)

This is surprisingly fascinating! Thanks

[–]YourAlienOverlord 1ポイント2ポイント  (0子コメント)

Anyone else find this strangely arousing?

No? Just me? ...Ok.

[–]b_ng 0ポイント1ポイント  (0子コメント)

This uh, makes me like pills more.

[–]theghostmachine 0ポイント1ポイント  (0子コメント)

Is that last one a time-release drug?

[–]ninjaphysics 0ポイント1ポイント  (0子コメント)

Look at all that entropy.

[–]littleusagi 0ポイント1ポイント  (0子コメント)

While this is certainly interesting, I just kept getting horrible flashbacks of all the times I'd have to take a fast dissolving horse pill as a kid and it got stuck in the back of my throat before I could get it down.

[–]deepsixz 0ポイント1ポイント  (1子コメント)

similar, sharper video, plus dubstep - https://vimeo.com/80846420

[–]TOASTuh[S] 0ポイント1ポイント  (0子コメント)

Yeah that was a good video. I think the audio is Flux Pavilion.

[–]redisforever 0ポイント1ポイント  (0子コメント)

I should do something like this. I have all the necessary equipment. Are they dissolving in just regular water or something else?

[–]sokkrokker 0ポイント1ポイント  (0子コメント)

It's a like a pillow exploding! Sweet

Edit: pillow is just a pill saying ow

[–]rivermandan 0ポイント1ポイント  (2子コメント)

gross, I do not want that inside me

[–]TheJollyCrank 1ポイント2ポイント  (0子コメント)

Try watching a video of getting food digested

I don't want that inside me

I suppose you could just have pill phobia

[–]GrammarAnneFrank 0ポイント1ポイント  (0子コメント)

You sound like my ex.

[–]everypostepic -5ポイント-4ポイント  (5子コメント)

I know that some say the more yellow your pee is, the healthy you are. Is that why that one released that yellow/orange "dye"?

I've always wondered about pills that just force your urine to change colors from dye, and not because you were any healthier.

[–]arsenal09490 7ポイント8ポイント  (0子コメント)

The more yellow your pee is means you are more dehydrated, and therefore less healthy. Your pee should have a yellow tint if you are healthy.

[–]Knoxeh 1ポイント2ポイント  (3子コメント)

B12 Vitamins do exactly that, makes your pee super yellow/orange.

[–]coolkid5 0ポイント1ポイント  (2子コメント)

I take b12. Every day for headaches. Should I stop? Neurologist put me on them. I don't know what information to believe anymore.

[–]Knoxeh 0ポイント1ポイント  (0子コメント)

B12 has health benefits that is for sure, the yellow pee side effect is just your body removing the extra unused B12 from your system. It's quite normal and nothing you should be worried about.

[–]Lifeguard2012 0ポイント1ポイント  (0子コメント)

No matter what I'd listen to your doctor over random people.

Maybe talk to him if you have concerns.

The yellow piss from taking B12 isn't you being dehydrated, it's just a natural side effect of the pill.