Omega-3 fatty acids are beneficial for the improvement of heart parameters
during exercise, help promote muscle recovery by reducing inflammation and reduce
the incidence of exercise induced bronchoconstriction. Walser et al., (2008)24 tested
the hypothesis that dietary supplementation with EPA (3 g/day) + DHA (2 g/day) would
be beneficial in the change in heart parameters during exercise. Twelve healthy
subjects received EPA/DHA and nine subjects received safflower oil as a control.
Both groups performed 20 minutes of bicycle exercise (ten minutes each at low and
moderate work intensity) before and after EPA/DHA or safflower oil treatment. Mean
arterial pressure, heart rate, stroke volume, cardiac output and systemic vascular
resistance were assessed before exercise and during both workloads. EPA/DHA augmented
increases in stroke volume and cardiac output and tended to attenuate decreases
in systemic vascular resistance during the moderate workload whereas safflower oil
treatment had no effects. The observed increases in stroke volume and cardiac output
with EPA/DHA supplementation imply that these fatty acids can increase oxygen delivery
during exercise, which may have beneficial clinical implications for individuals
with cardiovascular disease and reduced exercise tolerance. In another study, the
effects of fish oil supplementation and exercise were investigated in healthy, previously
sedentary males, ages 19-34. Thirty-two subjects were assigned to four groups: control,
fish oil, exercise, fish oil and exercise. The fish groups consumed 4000 mg/day
of omega-3 fatty acids. The exercise groups performed aerobic exercise for one hour
three times per week for ten weeks with pre- and post- values obtained for cholesterol,
triglycerides, HDL-cholesterol, LDL-cholesterol, maximal oxygen consumption, ventilatory
anaerobic threshold, percent body fat, and dietary composition of macronutrients
and polyunsaturated to saturated fat (P:S) ratio. Maximum oxygen consumption was
greater for the exercise groups (exercise and fish oil exercise) as compared to
the control group. Ventilatory anaerobic threshold was significantly greater with
fish oil, exercise, and their combination compared to control. This data indicates
an improvement in aerobic metabolism from aerobic exercise, alone or in combination
with fish oil, compared to controls.
Omega-3 fatty acids enhance exercise-induced increases in brachial artery
diameter and blood flow during rhythmic exercise, whereas safflower oil rich in
omega-6 fatty acids have no effect. Treatment with 5000 mg (2 g/d DHA and 3 g/d
EPA) of omega-3 fatty acids enhanced brachial artery blood flow and conductance
during exercise. In another study 18 white men with a history of myocardial infarction
and ejection fractions were randomized to placebo or omega-3 fatty acids (585 mg
DHA and 225 mg EPA) for two, four-month periods in a crossover design. At the end
of each period, heart rate, heart rate variability, and rate of heart rate recovery
after exercise were determined, as were effects on arterial compliance, blood pressure,
cardiac function, and fasting serum levels of lipids and inflammatory markers. Omega-3
fatty acids decreased heart rate at rest from 73+/-13 to 68+/-13 beats/minute and
improved 1-minute heart rate recovery after exercise. Heart rate variability in
the high-frequency band increased, but no change was noted in overall heart rate
variability.
The immune system of athletes is affected by intensity and duration of exercise.
Exhausting activities tend to produce adverse changes in immune parameters such
as total leukocytes, number of natural killer cells, lymphocyte count, helper-to-suppressor
cell ratio, proliferative response to a mitogen, and others35. Furthermore, during
exercise, there is an increase in the generation of superoxide radicals in the lipid
bilayers of muscle mitochondria, and trauma to the muscles16. Unaccustomed eccentric
exercise causes muscle damage that presents as delayed soreness, strength and range
of motion loss, swelling, and increased passive stiffness. These symptoms reduce
the ability to exercise and might be harmful if further exercise is continued36.
Excessive radical formation and trauma during high-intensity exercise leads to a
state of inflammation that is made worse by the increased amounts of omega-6 found
in the Western diet.
The effects of placebo or a dietary supplement containing mixed tocopherols,
flavonoids, and the omega-3 fatty acid DHA on exercise-induced markers of cell damage
and the inflammatory mediators C-reactive protein (CRP) and interleukin-6 (IL-6)
in 40 healthy, nonsmoking, untrained males for 14 days was investigated37. Blood
samples were collected on day 0 (baseline), day 7 (eccentric exercise-induced injury),
day 10, and day 14. Eccentric arm curl exercise was used to induce an acute phase
injury response as evidenced by significant increases in creatine kinase, lactate
dehydrogenase, and pain, as well as a decreased range of motion three days after
the exercise. There were significant group differences for IL-6 and C-reactive protein
and the authors concluded that exercise-induced inflammation, evaluated by changes
in IL-6 and C-reactive protein, were significantly reduced by the omega-3 fatty
acid containing dietary supplement.
We confirm that FREZZOR is a PROPRIETARY BLEND 150mg soft-gel cap that contains
pure greenlip mussel oil. The exact amount is proprietary information that we cannot
disclose. We use NO fillers, NO preservatives, and NO carriers.
Firstly, greenlip mussel oil contains over 33 different fatty acid groups
(lipid groups). Within the greenlip mussel fatty acid family there are approximately
18 well represented omega-3 structures in both the triglyceride and phospholipids'
forms. Two of these structures are better known than others, namely EPA and DHA.
EPA and DHA are not a measure of how effective a product is. These are just
two common figures given by unethical companies in order to convince consumers that
their product is the one to buy and use. This is a very simplistic approach that
has no scientific merit or basis.
Effectiveness of a product has nothing to do with the very simplistic approach
of how much EPA and DHA is actually in a product, but rather the synergistic results
that both these compounds (EPA and DHA) help to provide combined with a large number
of other forms of omega-3s found in the greenlip mussel in the correct ratios and
structures. What this means in very specific terms is the wellness benefit experienced
and the superior effectiveness is due to the unique combination and structure of
the omega-3s found in the greenlip mussel. This unique ratio and collection of omega-3,
6’s, 7’s and 9’s structures are not found in salmon, krill, cod, or anywhere else
in nature and due to the FREZZOR proprietary extraction process are fully bio available
in exactly the same ratios as nature designed greenlip mussels making them a complete
, balanced complex of lipids. Greenlip mussel oil is significantly more effective
than any other natural form of omega-3s on the planet in reducing inflammation.
Results always speak louder than words or figures and if anyone takes the
time to research the benefits of using greenlip mussel extract as a source of omega-3s
they will be quickly convinced that this is the right approach in comparison to
other natural sources of omega-3s.
The reason that FREZZOR provides a superior wellness experience to other
products containing greenlip mussel extract is due to a number of steps in the treatment
of the raw material and the unique proprietary processes used in FREZZOR's production.
The result of these combined proprietary processes is an extract that contains a
lot more "polar" omega-3s, in particular in the phospholipids' form than any other
greenlip mussel extract. These "polar" forms of omega-3s which include the well-known
DHA and EPA (which can be either "polar" and "non-polar") have been shown to be
more readily available (bio-available) to form the necessary bonds with cells within
the human body to provide therapeutic efficacy.
This can be seen to be the case in a very simplistic manner with sources
of fish oil such as cod and salmon that have undergone a refining process called
esterification that increases the amount of EPA and DHA -synthetically in order
to advertise a higher than natural EPA and DHA figure in order to convince the ill-informed
consumer that a particular product is superior. There is less benefit from these
esterified fish oils than from fish oils in their natural state, in fact some countries
have banned this process for human consumption on the basis of the poor uptake into
the body and the confusion it creates in the market-place.