HomeImprovement 内の Brain_Doc82 によるリンク Gutter Installation/Fascia Question

[–]Brain_Doc82[S] 0ポイント1ポイント  (0子コメント)

I actually went back and pulled up the inspection report, because this was something the inspector brought up. It is not drip edge flashing.

HomeImprovement 内の Brain_Doc82 によるリンク Inside Mount vs. Outside Mount Blinds

[–]Brain_Doc82[S] 0ポイント1ポイント  (0子コメント)

Thanks a bunch for the response. I think I'm understanding what you're saying. I've added a few more pictures.

http://imgur.com/a/LN65b

When I look I don't think there is any cove molding on the top part of the window. The caulking directly meets the window and the trim (I think?). I added a few more pictures that shows with the hardware. Do you think there is different hardware I can get or an adapter or something?

askscience 内の AutoModerator によるリンク Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

[–]Brain_Doc82 12ポイント13ポイント  (0子コメント)

One of my favorite stories of this type is Ralph Steinman. In the 1970's he discovered dendritic cells and proposed that they had a unique role in activating T-Cells and therefore were involved in the immune response. He was criticized for years before eventually demonstrating he was right with further research. In 2011 he won the Nobel Prize in Medicine for his work.

askscience 内の AutoModerator によるリンク Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

[–]Brain_Doc82 2ポイント3ポイント  (0子コメント)

Neuro(psych): What does current research say about the causes and nature of autism spectrum disorder? My understanding is that it is probably a collection of related disorders that can occur in different combinations, and are tied to numerous genetic markers. Is this accurate?

Yes. One newer are of very convincing research in the past few years is that paternal age at conception links quite highly to autism. The resulting theory is then that there are problems with the sperm that the father produces that may lead to the prodromal syndrome of autism, at least in some cases.

askscience 内の AutoModerator によるリンク Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

[–]Brain_Doc82 1ポイント2ポイント  (0子コメント)

Psychostimulants will generally produce a reliable benefit to cognitive functioning in most individuals (if dosed correctly). However, there are a lot of side effects, even at proper dosing, that makes using them in the long term for healthy individuals an unwise thing in my professional opinion.

askscience 内の AutoModerator によるリンク Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

[–]Brain_Doc82 0ポイント1ポイント  (0子コメント)

I assume by "short-circuit" you mean stop the amygdala from activating when the fight-flight response isn't needed (aka, pathological anxiety disorders)? If so, then medications are the quickest fix. However, in general they are not an ideal long term solution. Remember Jurassic Park? "Life will find a way"? The amygdala is very similar, and will find a way. Pharmaceutically suppressing the amygdala will eventually lead to a reduction in the threshold for an anxiety response, and can even lead to a greater anxiety response, or what we might call rebound anxiety. The best long term solution for managing anxiety disorders is cognitive and behavioral therapy techniques.

askscience 内の OnSpeakerCrab によるリンク Can a person lose their ability to form long-term memories, and what would their life be like?

[–]Brain_Doc82 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Yes. The most famous example is Henry Molaison, previously known as "Patient HM".

http://en.wikipedia.org/wiki/Henry_Molaison

askscience 内の dirtywhitehat によるリンク So hear me out ..Ok WHAT exactly causes Prion diseases?! Such as CJB or BSE. All I can find is "how it is transmitted"

[–]Brain_Doc82 1ポイント2ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

My expertise of prion disease is far more on the clinical detection and treatment side of things than the pathogenesis. I can recommend that James Mastrianni at University of Chicago is considered a leading clinical research expert on the topic. Definitely a place to start. Other than that, I would use pubmed and google scholar to focus on actual science lit and use terms like sporadic prion disease, prion pathogenesis, prion pathology, etc. Prion disease is extremely rare, and progresses so rapidly after diagnosis that it is very difficult to study.

askscience 内の dirtywhitehat によるリンク So hear me out ..Ok WHAT exactly causes Prion diseases?! Such as CJB or BSE. All I can find is "how it is transmitted"

[–]Brain_Doc82 3ポイント4ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Believe it or not, we now think that the majority of human CJD cases are sporadic and not transmitted. Meaning that there is an initial group of proteins that misfold, possibly without any exposure. We don't know what causes the misfolding in the first place. Maybe food exposure, maybe genetic, maybe environmental exposure, maybe ?? Look up Sporadic Prion Disease.

askscience 内の [deleted] によるリンク Why doesn't a new born baby come out all shrivelled due to sitting in water for 9 months straight?

[–]Brain_Doc82[M] 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

askscience 内の [deleted] によるリンク Why do Asian people have eyes with a "squint"?

[–]Brain_Doc82[M] 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

askscience 内の Zonevor によるリンク Because of iron in our blood, could holding or being near magnets for a while have unhealthy consequences?

[–]Brain_Doc82 1ポイント2ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

No, the iron in blood is not ferromagnetic.

askscience 内の Dogsafe によるリンク Does music in minor key sound sad/unsettling because of culture (I've grown up hearing minor key in sad/unsettling scenes in movies etc) or is it something inherent?

[–]Brain_Doc82[M] 26ポイント27ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Please remember that this is /r/askscience. Any answers to the question should be appropriately sourced/cited. This is not the place for anecdotes, guesses, or speculation.

Thanks, have a wonderfully scientific day!

askscience 内の az55za によるリンク Can someone have HPPD (Hallucinogen persisting perception disorder) without prior drug use?

[–]Brain_Doc82 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

No, they can't.

askscience 内の derekfor_real によるリンク What could cause someone without epilepsy to have recurring seizures?

[–]Brain_Doc82[M] 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Your post violates our medical advice policy and is removed, but I have to correct this for you: Epilepsy = recurrent seizures. If a person has more than one unprovoked seizure, they have epilepsy.

askscience 内の Therbin によるリンク How does OCD work on a neurological level?

[–]Brain_Doc82 7ポイント8ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Usually between 2-4 volts, pulsing. Though there are different methods, current controlled vs. voltage controlled systems, the former having some advantages. We focus it by putting the electrode where we want it in the brain. There are multiple electrodes and we can pick which ones we want on and at what rate, voltage, etc.

Edit: Picture. http://2.bp.blogspot.com/-b6I7QWLwfyI/TwtMUnL2RkI/AAAAAAAAT-A/3u6_XCkZIxo/s400/deep-brain-stimulation.jpg

askscience 内の Therbin によるリンク How does OCD work on a neurological level?

[–]Brain_Doc82[M] 91ポイント92ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Please remember that this is /r/askscience. Any answers to the question should be appropriately sourced/cited. This is not the place for anecdotes, guesses, or speculation. Please do not share your own experiences with OCD.

Thanks, have a wonderfully scientific day!

blog 内の cupcake1713 によるリンク What's that, Lassie? The old defaults fell down a well?

[–]Brain_Doc82 1ポイント2ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

Great point, and something we do try to keep an eye on (though it can be tough). If someone wants to ask a repeat question because a previous thread had an insufficient answer, we would encourage them to explain that they're looking for a more in depth/expansive/accurate answer than the ones that have been given in previous threads. We are very receptive to that.

cigars 内の Brain_Doc82 によるリンク Early Mold Advice-Save the Sticks???

[–]Brain_Doc82[S] 1ポイント2ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

This should serve as a reminder to everyone why you don't put water in your humidor with your cigars, ever.

Lesson learned. Thankfully the lesson wasn't too harsh this time!

askscience 内の lombarda によるリンク How can scientists say what a person (Or an animal?) is dreaming about?

[–]Brain_Doc82 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

They (we) can't.

cigars 内の Brain_Doc82 によるリンク Temporary Storage Advice for Groomsmen Gifts

[–]Brain_Doc82[S] 0ポイント1ポイント  (0子コメント)

ごめんなさい。これは既にアーカイブしてあり、もう投票はできません。

My respect?? I gotta remember that saying "You win" can be dangerous in a subreddit where contests and gifts are abundant...