Cialis is appealing to more men in their late years because of its long lasting effect. But, only a few of these men know how this drug all started. In this article, one will know more about the humble beginnings of this wonderful medication.

Basically, the production of Cialis started when GlaxoSmithKline who was then Glaxo Wellcome, partnered with the ICOS Company in 1991. Two years after, ICOS began observing a chemical compound known as IC351, a Phosphodiesterase type 5 (PDE5) inhibitor. Then, in 1994, Pfizer who was also studying another chemical substance that inhibits PDE5, discovered that Sildenafil can also treat erectile dysfunction in men as much as it can help treat cardiovascular diseases.

Pfizer’s new observation on the PDE5 inhibitor, Sildenafil led to ICOS’s finding that IC351 has also a potential in curing erectile dysfunction. So, in the same year, ICOS decided to get a patent for the IC351 and conduct further studies with it. In 1995, ICOS began the first phase of the series of necessary clinical trials for the substance. After two years, the company initiated the second and third phases of their clinical trials. They were indeed successful in their quest because in the same year, the company obtained the approval of the Food and Drug Administration or FDA.

But, the path for Cialis is not easy. After ICOS has acquired FDA’s approval, GlaxoSmithKline dropped its partnership with the company in 1996. Because of this, ICOS has to go solo with their launching of Cialis into the market. Good thing, the Eli Lily and Company came into the picture in 1998. With the partnership of these two companies, they tried to promote Tadalafil (the generic name for IC351) as a medication for erectile dysfunction. In addition, both companies registered again the compound IC351 at FDA under the name of their new partnership in 2000.
In 2002, the Lily ICOS partnership listed to the American Urological Association (ARU) its newest finding. That’s because their recent observation of Tadalafil or Cialis shows that the medication can work up to 36 hours. This is really a major breakthrough in the treatment of erectile dysfunctions in men because other similar drugs reported to last for just four hours.

Because of the success of Cialis in the market, the Eli Lily and Company decided to gain significant influence on ICOS by acquiring the company for 2.3 billion USD. Under the new management, Cialis maintained its brand name in the market. Also, further researches about the medication were made. In 2011, these studies become fruitful as Cialis was proven to treat another disorder in men known as the Benign Prostatic Hyperplasia.

The development of Cialis is really a product of an unending research. In fact, the Eli Lily and Company continues to find new potentials in Tadalafil. Today, the researchers of the drug continue to reap the results of their diligence and hard work. That’s because, the drug was able to gain the trust of men who have actually tried it.

Erectile dysfunction drugs are one of the biggest phenomena to hit the medical world in recent years. These drugs are capable of endowing those who consume it with bigger, stronger erections, resulting into better bedroom performance. These lightning in a bottle drugs are selling like hotcakes because it gives men a new level of vigor and confidence. And while there are other drugs out there that are possibly more popular, perhaps none out there can make the same claims as Cialis. This article will talk about some basics you need to know about Cialis.

Cialis is the product name of the drug Tadalafil, a drug developed jointly by the ICOS Corporation and Eli Lilly and Company. This drug is classified as a phosphodiesterase (PDE) inhibitor, not unlike its counterparts in the erectile dysfunction drug market, sildenafil (better known as Viagra) and vardenafil (better known as Levitra). There are some things these drugs have in common, and there are also some things that make Cialis such a unique and standout product.

So what are the things that make Cialis similar with other erectile dysfunction drugs? Just like Viagra, Cialis is also very well-known to be used as treatment for those who have cardiovascular problems. In particular, it’s being used as a treatment for pulmonary artery hypertension. By relaxing the walls of the pulmonary artery, flow resistance is reduced, resulting into the lowering of blood pressure. Also, it’s being used as a treatment for a prostate condition called benign prostatic hyperplasia. Last but not least, Cialis is similar with other erectile dysfunction drugs in the sense that it can be consumed anytime the person needs it.

But there are also some unique characteristics that make Cialis stand out from the competition. For example, compared to other PDE inhibitors, it requires much lower dosages for it to be effective. For instance, Viagra is available at dosages ranging from 25-100mgs. But with Cialis, the most potent variant of it is 20mgs. Such small and concentrated amount is a hallmark to this drug’s extreme potency. More about its potency, it’s reputed to be still effective 36 hours after taking it. Because of this, Cialis has earned the nickname “The Weekend Pill”.

As you would probably know by now, being a PDE inhibitor, Cialis works in a similar way with other PDE inhibiting drugs such as Viagra and Levitra. This is because by inhibiting PDE, it causes the relaxation of the muscles of the arterial walls. This relaxation improves blood flow, causing both the relieving of pulmonary arterial pressure and the better filling up of blood by the penis. But there’s something that makes Cialis a much more potent drug: its longer half-life. Tadalafil is used up at a much slower rate because of its 17-hour half-life. It’s this long half-life that allows it to be effective for longer periods than other erectile dysfunction drugs.

Those are just some of the interesting info that makes Cialis such a compelling drug to take. Taking the concept of the erectile dysfunction drug to new heights, its efficacy is unlike just about anything else on the market today.

You don’t have to deprive yourself of something that gives you happiness and satisfaction just because you are suffering from something that affects one in ten men. While impotence is becoming a common problem in men these days, many companies keep on improving their products in order to address the problem and provide even temporary help to those who are in need.

Among the best medicines that is available in the market these days, which can help you with this kind of problem is Cialis. This PDE5 inhibitor is also referred to as Tadalafil. It is important to take note though that the drug is effective when taken 30 minutes before you indulge in a sexual intercourse. This is not intended and will not work as a stimulant to increase your sexual desire.

Prescription Medicine

Cialis is a prescription medicine. Before you decide on anything, it is best that you talk with your partner regarding the plan. There are some people who shy away from opening up that they are suffering from erectile dysfunction, even to professionals. You will have an easier time addressing and facing the problem if you will tackle this with the support of your partner.

You can view or opt to download and print the Doctor Discussion Guide about this drug, which is available on websites that sell the product. This way, you will be prepared on what to tell your doctor when asked about your background and other health-related questions. This drug is intended to treat benign prostatic hyperplasia or BPH and erectile problems. Once you are done going through the guide, you can then set an appointment with your doctor.

Learn More about Cialis

If you are still undecided about whether or not you ought to get your doctor’s prescription for this drug, here are some vital facts that you have to be aware of. First, this is not intended to cure your dysfunction. This can only provide a temporary solution and you have to take it again the next time that you will indulge in another sexual activity in the same manner that you have taken the drug before. This also does not provide any kind of protection from sexually transmitted diseases, nor does it work as birth control for men. This will not increase your desires or sexual urges.

There are certain side effects that are experienced by a few people who have taken this drug. This is the reason why it is safe to talk with your doctor from the start, so that you can get in touch with them and ask for help if ever you encounter some of these uncommon side effects.

For one, there are reported instances of sudden decrease of hearing and vision after taking the drug. There are also those who felt dizzy and heard ringing in the ears as a result. These side effects are temporary, so you need not panic if you experience such. You only have to wait a while, but if it has been hours already and you are still experiencing these, it is best that you go to your doctor to seek help.