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Mitochondrial Disease Deal in Japan

Privately held Edison Pharmaceuticals Inc. wooed a big pharma partner, inking an R&D and commercialization agreement with Dainippon Sumitomo Pharma Co. Ltd. (DSP) to develop lead program EPI-743 and follow-on molecule EPI-589 in Japan.

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Dementia, Normal Brain Activity Both Cause DNA Damage: Study

Scientists have discovered that normal brain activity induces DNA damage, and that such damage is induced more strongly, and repaired more slowly, in the brains of mice with Alzheimer's disease. The findings suggest new possibilities for fighting neuronal damage in Alzheimer's disease, and such DNA breaks may also be a newly discovered mechanism of memory storage under normal circumstances.

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