2012 CRE Toolkit - Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE)
Carbapenem-resistant Enterobacteriaceae (CRE) are a serious threat to public health. Infections with CRE are difficult, and in some cases impossible, to treat and have been associated with mortality rates up to 50%(1). Due to the movement of patients throughout the healthcare system, if CRE are a problem in one facility, then typically they are a problem in other facilities in the region as well. To help protect patients and prevent transmission, CDC has released a CRE toolkit which expands on the 2009 CDC recommendations and continues to be updated as new information becomes available.
Table of Contents
- Introduction
- Background
- Definitions
- Part 1: Facility-level CRE Prevention
- Part 2: Regional CRE Prevention: Recommended Strategies for Health Department Implementation
- Public Health Engagement
- Regional Surveillance for CRE
- Regional Prevention Strategies
- Appendix A: Previous and Current Clinical and Laboratory Standards Institute Interpretive Criteria for Carbapenems and Enterobacteriaceae
- Appendix B: General Approach to Carbapenem-resistant Enterobacteriaceae(CRE) Control in Facilities that Rarely or Have Not Identified CRE
- Appendix C: Example of a Survey for Infection Preventionists
- Survey of Healthcare Facilities for Carbapenem-resistant Enterobacteriaceae (CRE)
- Selected References
- Refers to: Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:1099-106.
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