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Dynamics and memory of heterochromatin in living cells.

Hathaway NA, Bell O, Hodges C, Miller EL, Neel DS, Crabtree GR. Cell. 2012 Jun 22; 149(7):1447-60

Iannis Aifantis and Panagiotis Ntziachristos, HHMI/New York University School of Medicine, NY, USA. F1000 Developmental Biology

30 Jul 2012 | Good for Teaching, New Finding, Technical Advance

In this excellent study, Crabtree and colleagues developed a powerful system to study the kinetics and dynamics of heterochromatin formation. Furthermore, they characterized the relationship between the heterochromatin formation and the gene expression outcome and delineated the epigenetic inheritance of the expression patterns.

The...

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