業績

Mikogai A, Yanagisawa J, Yasuzawa-Tanaka K, Murayama A
The nucleolar protein NML regulates hepatic ATP levels during liver regeneration after partial hepatectomy.
Biochem Biophys Res Commun. 390(3):591-596 (2009).

Takemoto A, Maeshima K, Ikehara T, Yamaguchi K, Murayama A, Imamura S, Imamoto N, Yokoyama S, Hirano T, Watanabe Y, Hanaoka F, Yanagisawa J, Kimura K.
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A.
Nat Struct Mol Biol. (2009) 16(12):1302-1308.


Akaogi K, Nakajima Y, Ito I, Kawasaki S, Oie S, Murayama A, Kimura K, Yanagisawa J.
KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ER alpha. 
Oncogene. 28, 2894-2902 (2009)

Kajiro M, Hirota R, Nakajima Y, Kawanowa K, So-Ma K, Ito I, Yamaguchi Y, Ohie SH, Kobayashi Y, Seino Y, Kawano M, Kawabe YI, Takei H, Hayashi SI, Kurosumi M, Murayama A, Kimura K, Yanagisawa J. 
The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways.
Nat Cell Biol. 11, 312-319(2009)

Murayama A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, Kuroda T, Oie S, Daitoku H, Okuwaki M, Nagata K, Fukamizu A, Kimura K,  Shimizu  T, Yanagisawa J. 
Epigenetic control of rDNA loci in response to intracellular energy status.
Cell 133,627-639 (2008)

Komatsu Y, Ito I, Wayama M, Fujimura A, Akaogi K, Machida H, Nakajima Y, Kuroda T, Ohmori K, Murayama A, Kimura K, Yanagisawa J.
PPARγ ligands suppress the feedback loop between E2F2 and cyclin-E1.
Biochem Biophys Res Commun. 370(1), 145-148 (2008)

Takemoto A, Murayama A, Katano M, Urano T, Furukawa F, Yokoyama S, Yanagisawa J, Hanaoka F, Kimura K.
Analysis of the role of Aurora B on the chromosomal targeting of condensin I.
Nucl. Acids Res. 35, 2403-12 (2007).

Kim M, Fujiki R, Murayama A, Kitagawa H, Yamaoka K, Yamamoto Y, Mihara M, Takeyama K, Kato S. 
1{alpha},25(OH)2D3 -induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter.
Mol Endocrinol. 21, 334-342 (2007)

Tateishi Y, Sonoo R, Sekiya Y, Sunahara N, Kawano M, Wayama M, Hirota R, Kawabe Y, Murayama A, Kato S, Kimura K, Yanagisawa J. 
Turning off estrogen receptor beta-mediated transcription requires estrogen-dependent receptor proteolysis.
Mol Cell Biol. 26(21):7966-7976 (2006)

Murayama A, Sakura K, Nakama M, Yasuzawa-Tanaka K, Fujita E, Tateishi Y, Wang Y, Ushijima T, Baba T, Shibuya K, Shibuya A, Kawabe Y, Yanagisawa J. 
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory.
EMBO J. 25, 1081-1092. (2006)

Murayama A, Kim M, Yanagisawa J, Takeyama K, Kato S. 
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. 
EMBO J. 23, 1598-1608 (2004)

Tateishi Y, Kawabe Y, Chiba T, Murata S, Ichikawa K, Murayama A, Tanaka K, Baba T, Kato S, Yanagisawa J. 
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor. 
EMBO J. 23, 4813-4823 (2004)

Fujita T, Kobayashi Y, Wada O, Tateishi Y, Kitada L, Yamamoto Y, Takashima H, Murayama A, Yano T, Baba T, Kato S, Kawabe Y, Yanagisawa J. 
Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.
J. Biol. Chem. 278,26704-26714 (2003)

Kato S, Yoshizawa T, Kitanaka S, Murayama A, Takeyama K. 
Molecular genetics of vitamin D-dependent hereditary rickets.
Horm Res. 57(3-4), 73-78 (2002)

Matsui D, Sakari M, Sato T, Murayama A, Takada I, Kim M, Takeyama K, Kato S. Transcriptional regulation of the mouse steroid 5alpha-reductase type II gene by progesterone in brain.
Nucl. Acids Res. 30(6), 1387-1393 (2002)

Kitanaka S, Takeyama K, Murayama A, Kato S. 
The molecular basis of vitamin D-dependent rickets type I.
Endocr J. 48(4), 427-432 (2001)

Inui N, Murayama A, Sasaki S, Suda T, Chida K, Kato S, Nakamura H. 
Correlation between 25-hydroxyvitamin D3 1 alpha-hydroxylase gene expression in alveolar macrophages and the activity of sarcoidosis.
Am. J. Med. 110(9), 687-693 (2001)

Kodera Y, Takeyama K, Murayama A, Suzawa M, Masuhiro Y, Kato S. 
Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators.
J. Biol. Chem. 275(43), 33201-33204 (2000)

Kitanaka S, Murayama A, Sakaki T, Inoue K, Seino Y, Fukumoto S, Shima M, Yukizane S, Takayanagi M, Niimi H, Takeyama K, Kato, S.
No enzyme activity of 25-hydroxyvitamin D3 1alpha-hydroxylase gene product in pseudovitamin D deficiency rickets, including that with mild clinical manifestation.
J Clin Endocrinol Metab. 84(11), 4111-4117 (1999)

Kato S, Takeyama K, Kitanaka S, Murayama A, Sekine K, Yoshizawa T. 
In vivo function of VDR in gene expression-VDR knock-out mice.
J Steroid Biochem Mol Biol. 69(1-6), 247-251 (1999)

Takeyama K, Masuhiro Y, Fuse H, Endoh H, Murayama A, Kitanaka S, Suzawa M, Yanagisawa J, Kato S. 
Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog. 
Mol Cell Biol. 19(2), 1049-1055 (1999)

Murayama A, Takeyama K, Kitanaka S, Kodera Y, Kawaguchi Y, Hosoya T, Kato S.  Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone,calcitonin, and 1alpha,25(OH)2D3 in intact animals. 
Endocrinology. 140(5), 2224-2231 (1999)

Murayama A, Takemori S, Umazume Y. 
A Novel modulator of phosphate transport of erythrocytes suggested by Nuclear Magnetic Resonance. 
Jikeikai Med J.  46, 199-207 (1999)

Murayama A, Takeyama K, Kitanaka S, Kodera Y, Hosoya T, Kato S. 
The promoter of the human 25-hydroxyvitamin D3 1 alpha-hydroxylase gene confers positive and negative responsiveness to PTH, calcitonin, and 1 alpha,25(OH)2D3. 
Biochem Biophys Res Commun.  249(1), 11-16 (1998)

Kato S, Yanagisawa J, Murayama A, Kitanaka S, Takeyama K. 
The importance of 25-hydroxyvitamin D3 1 alpha-hydroxylase gene in vitamin D-dependent rickets.
Curr Opin Nephrol Hypertens. 7(4), 377-383 (1998)

Kitanaka S, Takeyama K, Murayama A, Sato T, Okumura K, Nogami M, Hasegawa Y, Niimi H, Yanagisawa J, Tanaka T, Kato S. 
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets.
N Engl J Med.  338(10), 653-661 (1998)

村山明子、武山健一、北中幸子、加藤茂明
「ビタミンD3 1a-水酸化酵素の遺伝子発現制御機構の解析」 
『日本骨代謝学会誌』 137-141, (1999)(第16回日本骨代謝学会奨励賞基礎賞受賞論文)


受賞
柳澤(村山)明子.若手科学者賞,科学技術分野文部科学大臣表彰,2009.4.14.