Dy, P. , P. Smits, A. Silvester, A. Penzo-Méndez, B. Dumitriu, Y. Han, C. A. de la Motte, D. M. Kingsley, and V. Lefebvre (2010)."Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage." Developmental Biology 34:346-59. |
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Kahn, J., Y. Shwartz, E. Blitz, S. Krief, A. Sharir, D.A. Breitel, R. Rattenbach, F. Relaix, P. Maire, R.B. Rountree, D.M. Kingsley, and E. Zelzer (2009). "Muscle Contraction Is Necessary to Maintain Joint Progenitor Cell Fate." Developmental Cell 16 (5): 734-743. |
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Guenther, C., L. Pantalena-Filho, and D.M. Kingsley (2008). "Shaping skeletal growth by modular regulatory elements in the Bmp5 gene." PLoS Genetics 4(12): e1000308 doi:10.1371/journal.pgen.1000308 |
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Menke, D.B., C. Guenther, and D.M. Kingsley (2008). "Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs." Development 135(15):2543-2553. |
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Ho, A. M., P. C. Marker, H. Peng, A. J. Quintero, D. M. Kingsley and J. Huard (2008). "Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation." BMC Dev Biol 8: 35. |
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Koyama, E., Y. Shibukawa, M. Nagayama, H. Sugito, B. Young, T. Yuasa, T. Okabe, T. Ochiai, N. Kamiya, R. B. Rountree, D. M. Kingsley, M. Iwamoto, M. Enomoto-Iwamoto and M. Pacifici (2008). "A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis." Dev Biol 316: 62-73. |
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Koyama, E., T. Ochiai, R.B. Rountree, D.M. Kingsley,
M. Enomoto-Iwamoto, M. Iwamoto, M. Pacifici (2007). "Synovial Joint
Formation during Mouse Limb Skeletogenesis." Roles of Indian Hedgehog
Signaling. Ann. N.Y. Acad. Sci. 1116, 100–112. |
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Miller, C. T., S. Beleza, A. A. Pollen, D. Schluter,
R. A. Kittles, M. D. Shriver and D. M. Kingsley (2007). "cis-Regulatory
changes in Kit Ligand expression and parallel evolution of pigmentation
in sticklebacks and humans." Cell 131: 1179-1189. |
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Feldman, G. J., R. V. Patel, P. Billings, R. J. Caron,
C. Guenther, D. M. Kingsley, F. S. Kaplan and E. M. Shore (2007).
"Over-expression of Bmp4 and Bmp5 in a child with axial skeletal abnormalities
and heterotopic ossification: a new syndrome." Am J Med Genet: 143A:
699-706. |
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Gurley, K. A., R. J. Reimer and D. M. Kingsley (2006).
"Biochemical and genetic analysis of ANK in arthritis and bone disease."
Am. J. Hum. Genet. 79: 1017-1029. |
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Gurley, K., H. Chen, C. Guenther, E. Nguyen, R. B. Rountree,
M. Schoor and D. M. Kingsley (2006). "Mineral formation in joints
caused by complete or joint-specific loss of ANK function." J Bone
Miner Res 21: 1238-1247. |
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Portnoy, M. E., K. J. McDermott, A. Antonellis, E. H.
Marguiles, A. B. Prasad, N. C. S. Program, D. M. Kingsley, E. D. Green
and D. P. Mortlock (2005). "Detection of potential Gdf6 regulatory
elements by multi-species sequence comparisons and identification
of a skeletal joint enhancer." Genomics 86: 295-305. |
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Rountree, R. B., M. Schoor, H. Chen, M. E. Marks, V.
Harley, Y. Mishina and D. M. Kingsley (2004). "BMP receptor signaling
is required for postnatal maintenance of articular cartilage." PLOS
Biology 2: e355. |
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Settle, S. H., R. B. Rountree, A. Sinha, A. Thacker,
K. Higgins and D. M. Kingsley (2003). "Multiple joint and skeletal
patterning defects caused by single and double mutations in the mouse
Gdf6 and Gdf5 genes." Dev Biol 254: 116-130. |
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Mortlock, D. P., C. Guenther and D. M. Kingsley (2003).
"A general approach for identifying distant regulatory elements applied
to the Gdf6 gene." Genome Res 13: 2069-2081. |
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Pendleton, A., M. D. Johnson, A. Hughes, K. A. Gurley,
A. M. Ho, M. Doherty, J. Dixey, P. Gillet, D. Loeuille, R. McGrath,
A. Reginato, R. Shiang, G. Wright, P. Netter, C. Williams and D. M.
Kingsley (2002). "Mutations in ANKH cause chondrocalcinosis." Am J
Hum Genet 71(4): 933-940. |
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Nociti, F. H., Jr., J. E. Berry, B. L. Foster, K. A.
Gurley, D. M. Kingsley, T. Takata, M. Miyauchi and M. J. Somerman
(2002). "Cementum: a phosphate-sensitive tissue." J Dent Res 81(12):
817-821. |
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Thut, C. J., R. B. Rountree, M. Hwa and D. M. Kingsley
(2001). "A large-scale in situ screen provides molecular evidence
for the induction of eye anterior segment structures by the developing
lens." Dev Biol 231(1): 63-76. |
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Settle, S., P. Marker, K. Gurley, A. Sinha, A. Thacker,
Y. Wang, K. Higgins, G. Cunha and D. M. Kingsley (2001). "The BMP
family member Gdf7 is required for seminal vesicle growth, branching
morphogenesis, and cytodifferentiation." Dev Biol 234(1): 138-150. |
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Kingsley, D. M. (2001). "Genetic control of bone and
joint formation." Novartis Found Symp 232: 213-222; discussion 222-234,
272-282. |
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Clark, R. M., P. C. Marker, E. Roessler, A. Dutra, J.
C. Schimenti, M. Muenke and D. M. Kingsley (2001). "Reciprocal mouse
and human limb phenotypes caused by gain- and loss-of-function mutations
affecting lmbr1." Genetics 159(2): 715-726. |
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Ho, A., M. Johnson and D. M. Kingsley (2000). "Role
of the mouse ank gene in tissue calcification and arthritis." Science
289: 265-270. |
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DiLeone, R. J., G. A. Marcus, M. D. Johnson and D. M.
Kingsley (2000). "Efficient studies of long-distance Bmp5 gene regulation
using bacterial artificial chromosomes." Proc. Natl. Acad. Sci. (USA)
97: 1612-1617. |
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Clark, R. M., P. C. Marker and D. M. Kingsley (2000).
"A novel candidate for mouse and human preaxial polydactyly with altered
expression in limbs of Hemimelic extra toes mice." Genomics 67: 19-27. |
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Storm, E. E. and D. M. Kingsley (1999). "GDF5 coordinates
bone and joint formation during digit development." Dev. Biol. 209:
11-27. |
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Kingsley, D. M. (1998). Bone morphogenetic proteins
in the formation and repair of cartilage, bone, and joints. Skeletal
growth and development: clinical issues and basic science advances.
J. A. Buckwalter, M. G. Ehrlich, L. J. Sandell and S. B. Trippel.
Rosemont, IL, American Academy of Orthopaedic Surgeons: 87-98. |
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DiLeone, R. J., L. B. Russell and D. M. Kingsley (1998).
"An extensive 3' regulatory region controls expression of Bmp5 in
specific anatomical structures of the mouse embryo." Genetics 148:
401-408. |
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Marker, P. C., K. Seung, A. E. Bland, L. B. Russell
and D. M. Kingsley (1997). "Spectrum of Bmp5 mutations from germline
mutagenesis experiments in mice." Genetics 145: 435-443. |
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DiLeone, R. J., J. A. King, E. E. Storm, N. G. Copeland,
N. A. Jenkins and D. M. Kingsley (1997). "The Bmp8 gene is expressed
in developing skeletal tissue and maps near the achondroplasia locus
on mouse chromosome 4." Genomics 40: 196-198. |
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Storm, E. E. and D. M. Kingsley (1996). "Joint patterning
defects caused by single and double mutations in members of the bone
morphogenetic protein (BMP) family." Development 122: 3969-3979. |
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Mikic, B., M. C. H. van der Meulen, D. M. Kingsley and
D. R. Carter (1996). "Mechanical and geometric changes in the growing
femora of BMP-5 deficient mice." Bone 18: 601-607. |
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King, J. A., E. E. Storm, P. C. Marker, R. DiLeone and
D. M. Kingsley (1996). "The role of BMPs and GDFs in development of
region-specific skeletal structures." Annals New York Acad Sci 785:
70-79. |
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Mikic, B., M. C. H. van der Meulen, D. M. Kingsley and
D. R. Carter (1995). "Long bone geometry and strength in adult BMP-5
deficient mice." Bone 16: 445-454. |
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Marker, P. C., J. A. King, N. G. Copeland, N. A. Jenkins
and D. M. Kingsley (1995). "Chromosomal localization, embryonic expression,
and imprinting tests for Bmp7 on distal mouse chromosome 2." Genomics
28: 576-580. |
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Avraham, K. B., T. Hasson, K. P. Steel, D. M. Kingsley,
L. B. Russell, M. S. Mooseker, N. G. Copeland and N. A. Jenkins (1995).
"The mouse Snell's waltzer deafness gene encodes an unconventional
myosin required for structural integrity of inner ear hair cells."
Nat Genet 11(4): 369-375. |
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Storm, E. E., T. V. Huynh, N. G. Copeland, N. A. Jenkins,
D. M. Kingsley and S.-L. Lee (1994). "Limb alterations in brachypodism
mice due to mutations in a new member of the TGF-beta superfamily."
Nature 368: 639-643. |
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Kingsley, D. M. (1994). "The TGF-beta superfamily: new
members, new receptors, and new genetic tests of function in different
organisms." Genes and Development 8: 133-146. |
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Kingsley, D. M. (1994). "What do BMPs do in mammals?
Clues from the mouse short ear mutation." Trends Genet. 10: 16-21. |
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King, J. A., P. C. Marker, K. J. Seung and D. M. Kingsley
(1994). "BMP5 and the molecular, skeletal, and soft-tissue alterations
in short ear mice." Dev. Biol. 166: 112-122. |
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Imai, K. and D. M. Kingsley (1994). "Mouse chromosome
9." Mammalian Genome 5: S139-S153. |
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Kingsley, D. M. (1993). "Encylopedia of the mouse genome
III: Mouse chromosome 9." Mammal Genome 4: S136-S153. |
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Kingsley, D. M., A. E. Bland, J. M. Grubber, P. C. Marker,
L. B. Russell, N. G. Copeland and N. A. Jenkins (1992). "The mouse
short ear skeletal morphogenesis locus is associated with defects
in a bone morphogenetic member of the TGF-? superfamily." Cell 71:
399-410. |
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Kingsley, D. M. (1992). "Mouse Chromosome 9." Mammalian
Genome 3: S136-S152. |
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Kingsley, D. M. (1991). "Mouse Chromosome 9." Mammalian
Genome 1: S127-S145. |
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Copeland, N. G., C. M. Silan, D. M. Kingsley, N. A.
Jenkins, L. A. Cannizzaro, C. M. Croce, K. Huebner and J. E. Sims
(1991). "Chromosomal location of murine and human IL-1 receptor genes."
Genomics 9(1): 44-50. |
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Kingsley, D. M., E. M. Rinchik, L. B. Russell, H. P.
Ottiger, J. G. Sutcliffe, N. G. Copeland and N. A. Jenkins (1990).
"Genetic ablation of a mouse gene expressed specifically in brain."
EMBO J 9(395): 395-399. |
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Freeman, M., J. Ashkenas, D. J. G. Rees, D. M. Kingsley,
N. G. Copeland, N. A. Jenkins and M. Krieger (1990). "An ancient,
highly conserved family of cysteine-rich protein domains revealed
by cloning the type I and type II murine macrophage scavenger receptors."
Proc. Natl. Acad. Sci. USA 87: 8810-8814. |
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Dickinson, M. E., M. S. Kobrin, C. M. Silan, D. M.
Kingsley, M. J. Justice, D. A. Miller, J. D. Ceci, L. F. Lock, A.
Lee, A. M. Buchberg, L. D. Siracusa, K. M. Lyons, R. Derynck, B. L.
M. Hogan, N. G. Copeland and N. A. Jenkins (1990). "Chromosomal location
of seven members of the murine TGF-? superfamily suggests close linkage
to several morphogenetic mutant loci." Genomics 6: 505-520. |
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Ceci, J. D., D. M. Kingsley, C. M. Silan, N. G. Copeland
and N. A. Jenkins (1990). "An interspecific backcross linkage map
of the proximal half of mouse chromosome 14." Genomics 6(4): 673-678. |
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Regnier, D. C., C. A. Kozak, D. M. Kingsley, N. A. Jenkins,
N. G. Copeland, W. Y. Langdon and H. C. Morse (1989). "Identification
of two murine loci homologous to the v-cbl oncogene." J Virol 63:
3678-3682. |
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Krieger, M., P. Reddy, K. Kozarsky, D. Kingsley, L.
Hobbie and M. Penman (1989). "Analysis of the synthesis, intracellular
sorting, and function of glycoproteins using a mammalian cell mutant
with reversible glycosylation defects." Methods Cell Biol 32(57):
57-84. |
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Kingsley, D. M., N. A. Jenkins and N. G. Copeland (1989).
"A molecular genetic linkage map of mouse chromosome 9 with regional
localizations for the Gsta, T3g, Ets-1, and Ldlr loci." Genetics 123(165):
165-172. |
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Jenkins, N. A., M. C. Storbel, P. K. Seperack, D. M.
Kingsley, K. J. Moore, J. A. Mercer, L. B. Russell and N. G. Copeland
(1989). "A retroviral insertion in the dilute (d) locus provides molecular
access to this region of mouse Chromosome 9." Progr Nucl Acid Res
Mol Biol 36(207): 207-220. |
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Kozarsky, K., D. Kingsley and M. Krieger (1988). "Use
of a mutant cell line to study the kinetics and function of O-linked
glycosylation of low density lipoprotein receptors." Proc Natl Acad
Sci U S A 85(12): 4335-4339. |
|
Hobbie, L., D. M. Kingsley, K. F. Kozarsky, R. W. Jackman
and M. Krieger (1987). "Restoration of LDL receptor activity in mutant
cells by intercellular junctional communication." Science 235(4784):
69-73. |
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Kingsley, D. M., R. D. Sege, K. F. Kozarsky and M. Krieger
(1986). "DNA-mediated transfer of a human gene required for low-density
lipoprotein receptor expression and for multiple Golgi processing
pathways." Mol Cell Biol 6(7): 2734-2737. |
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Kingsley, D. M., M. Krieger and J. B. Holton (1986).
"Structure and function of low-density-lipoprotein receptors in epimerase-deficient
galactosemia [letter]." N Engl J Med 314(19): 1257-1258. |
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Kingsley, D. M., K. F. Kozarsky, M. Segal and M. Krieger
(1986). "Three types of low density lipoprotein receptor-deficient
mutant have pleiotropic defects in the synthesis of N-linked, O-linked,
and lipid-linked carbohydrate chains." J Cell Biol 102(5): 1576-1585. |
|
Kingsley, D. M., K. F. Kozarsky, L. Hobbie and M. Krieger
(1986). "Reversible defects in O-linked glycosylation and LDL receptor
expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant."
Cell 44(5): 749-759. |
|
Kingsley, D. M. and M. Krieger (1984). "Receptor-mediated
endocytosis of low density lipoprotein: somatic cell mutants define
multiple genes required for expression of surface-receptor activity."
Proc Natl Acad Sci U S A 81(17): 5454-5458. |
|
Krieger, M., J. Martin, M. Segal and D. Kingsley (1983).
"Amphotericin B selection of mutant Chinese hamster cells with defects
in the receptor-mediated endocytosis of low density lipoprotein and
cholesterol biosynthesis." Proc Natl Acad Sci U S A 80(18): 5607-5611. |
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