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Seasonal flu shot may increase H1N1 risk

Last Updated: Wednesday, September 23, 2009 | 10:03 PM ET

Across Canada, public health authorities are fiercely debating the idea of shortening, delaying or scrapping their seasonal flu vaccination campaign in favour of mass inoculation against H1N1.Across Canada, public health authorities are fiercely debating the idea of shortening, delaying or scrapping their seasonal flu vaccination campaign in favour of mass inoculation against H1N1. (Greg Baker/Associated Press)

Preliminary research suggests the seasonal flu shot may put people at greater risk for getting swine flu, CBC News has learned.

"This is some evidence that has been floated. It hasn't been validated yet, it's very preliminary," cautioned Dr. Don Low, microbiologist-in-chief at Mount Sinai Hospital in Toronto.

"This is obviously important data to help guide policy decisions. How can we best protect people against influenza?"

It's important to validate the information, which has not been peer reviewed, to make sure it's not just a fluke, and that the observation is confirmed elsewhere such as in the Southern Hemisphere, which just completed its seasonal flu season, or in the U.S. and UK.

Four Canadian studies involved about 2,000 people, health officials told CBC News. Researchers found people who had received the seasonal flu vaccine in the past were more likely to get sick with the H1N1 virus.

Researchers know that, theoretically, when people are exposed to bacteria or a virus, it can stimulate the immune system to create antibodies that facilitate the entry of another strain of the virus or disease. Dengue fever is one example, Low said.

No seasonal flu shot?

The latest finding raises questions about the order in which to get flu shots.

Across Canada, public health authorities are debating the idea of shortening, delaying or scrapping their seasonal flu vaccination campaign in favour of mass inoculation against H1N1.

The main reason is that H1N1 may be the dominant strain of influenza circulating when the fall flu season hits, meaning it could be a waste of time and resources to mount a seasonal flu vaccine campaign.

Health authorities in Quebec are considering cancelling or postponing seasonal flu shots for some groups, such as healthy, younger adults.

The Public Health Agency of Canada says it's up to provinces and territories to decide on when to roll out flu shots.

"We don't know with this year's flu shot how it interacts with the pandemic flu shot, so it's a worry," said Dr. Michael Gardam, director of infectious diseases prevention and control at the Ontario Agency for Health Protection and Promotion.

"It makes the decision-making a lot more complex," Dr. Perry Kendall, B.C.'s provincial health officer, said in Victoria. "It would be very nice to have information cut and dried, and very clear in advance in plenty of time to make the decisions. But that isn't unfortunately the world that we're living in."

In Thornhill, Ont., Melissa Cass, who usually gets an annual flu shot to protect herself, had been planning to get one this year for her one-year-old daughter, Aliya, as well.

"You have a baby, you sort of want to protect them from everything possible. So if you can protect them from some things, why not?" Cass said.

But this year, she may not get any shots.

"If I knew that it was a risk to get H1N1, I wouldn't get any of them," she told CBC News. "I would just be as I am and just, you know, take all the precautions I possibly can for flus, and that's it."

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Related

Video

CBC's Heather Hiscox interviews Dr. Donald Low, chief of microbiology at Toronto's Mt. Sinai Hospital (Runs: 9:07)
Play: Real Media »
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Ioanna Roumeliotis reports: Seasonal flu shot may increase H1N1 risk: early data (Runs: 3:09)
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Play: QuickTime »

Swine flu

Ready or not
Hygiene lessons to prevent school spread
Swine flu: FAQs
How it's unfolding: a timeline
Isolating the ill: when to quarantine
Map: Confirmed swine flu cases around the globe
Investigating swine flu: WHO's pandemic alert levels
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Will face masks protect you from the flu?
Inside CBC News: We are not renaming swine flu

In Depth

Pandemic preparation: dealing with infectious disease outbreaks
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How viruses mutate
Misconceptions about the flu
Tips for building your immune system
Fighting the flu
The 1918 flu epidemic
CBC Archives: Influenza - Battling the last great virus
CBC Archives: The swine flu fiasco

Stories

Flu shot plans vary across Canada
(Sept. 25, 2009)
Swine flu raises questions about sick leave policies
(Sept. 25, 2009)
Seasonal flu shot may increase H1N1 risk
(Sept. 23, 2009)
Swine flu hits Vancouver and island schools
(Sept. 23, 2009)
Swine flu protocol signed for First Nations
(Sept. 19, 2009)
Swine flu vaccines to fall short: WHO
(Sept. 18, 2009)
H1N1 vaccine in babies worries expert
(Sept. 17, 2009)
Swine flu outbreak hits Vancouver Island First Nations
(Sept. 17, 2009)
Fears over H1N1 flu rising in NWT community
(Sept. 17, 2009)
H1N1 vaccine priority groups released
Sept. 16, 2009
H1N1 vaccines get U.S. approval
Sept. 15, 2009
1 dose of Canada's H1N1 shot protects adults: company
Sept. 14, 2009
Address swine flu vaccine fears, doctor urges
Sept. 11, 2009
Vaccinate kids early to fight swine flu
Sept. 10, 2009
H1N1 infects cells deep in lungs
Sept. 10, 2009
Swine flu deaths top 2,800 worldwide
Sept. 4, 2009
Canada's swine flu vaccine coming in October
Sept. 3, 2009
Swine flu vaccine on schedule: health minister
Sept. 2, 2009
Flu vaccine plan will be too slow: CMAJ
August 31, 2009
Feds, First Nations leaders at odds on swine flu preparations
August 29, 2009
Swine flu vaccine funding boosted
August 27, 2009
Swine flu 'czar' needed: CMA Journal
August 17, 2009
Canada to order 50.4 million H1N1 vaccine doses
August 6, 2009
Universities brace for fall swine flu wave
July 30, 2009
Canadian swine flu vaccine set for October
July 17, 2009
Alcohol-based sanitizers for flu-hit First Nations delayed over substance abuse fears
June 23, 2009
WHO declares swine flu pandemic, no change in Canada's approach
June 11, 2009
Swine flu epidemic in decline: Mexico
May 3, 2009
No sustained spread of swine flu virus outside North America: WHO
May 2, 2009
Canada doing all that's needed to respond to swine flu: PM
April 30, 2009
WHO boosts pandemic alert level to 5
April 29, 2009

Video

Former patients tell their stories
What the World of Warcraft video game is teaching pandemic experts
Swine flu reality check with Dr. Michael Gardam with the Ontario Agency for Health Protection (4:25)
May 1, 2009

External Links

H1N1 Flu Virus surveillance from the Public Health Agency of Canada
Influenza A/H1N1 situation updates from the WHO
H1N1 Flu situation update from Centres for Disease Control

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